About: THE STUDY OF MOUSE MYOCARDIAL ISCHEMIC RESISTANCE AND RADICAL DAMAGE

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About: THE STUDY OF MOUSE MYOCARDIAL ISCHEMIC RESISTANCE AND RADICAL DAMAGE Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The heart is a strictly aerobic body with an energetically very demanding metabolism. Constant supply of oxygen is vital for its normal function. If the oxygen supply is stopped, such as coronary artery thrombotisation , or severely limited, such as stenosis, myocardial damage occurs due to hypoxia. The amount of hypoxic damage is dependent on the duration of ischemia and also on the resistance to myocardial oxygen deprivation. This resistance is conditioned by a number of mechanisms at both the biochemical and molecular levels. The aim of this work was to demonstrate UCP2 (-/-) animals resistant to ischemic damage - which we confirmed. Further evidence of free radical damage at the time and the expression of HIF ischemie. Free radical damage at the time of expression, we have demonstrated The heart is a strictly aerobic body with an energetically very demanding metabolism. Constant supply of oxygen is vital for its normal function. If the oxygen supply is stopped, such as coronary artery thrombotisation , or severely limited, such as stenosis, myocardial damage occurs due to hypoxia. The amount of hypoxic damage is dependent on the duration of ischemia and also on the resistance to myocardial oxygen deprivation. This resistance is conditioned by a number of mechanisms at both the biochemical and molecular levels. The aim of this work was to demonstrate UCP2 (-/-) animals resistant to ischemic damage - which we confirmed. Further evidence of free radical damage at the time and the expression of HIF ischemie. Free radical damage at the time of expression, we have demonstrated (en)
Title	THE STUDY OF MOUSE MYOCARDIAL ISCHEMIC RESISTANCE AND RADICAL DAMAGE THE STUDY OF MOUSE MYOCARDIAL ISCHEMIC RESISTANCE AND RADICAL DAMAGE (en)
skos:prefLabel	THE STUDY OF MOUSE MYOCARDIAL ISCHEMIC RESISTANCE AND RADICAL DAMAGE THE STUDY OF MOUSE MYOCARDIAL ISCHEMIC RESISTANCE AND RADICAL DAMAGE (en)
skos:notation	RIV/00064165:_____/11:10991!RIV12-MZ0-00064165
http://linked.open...avai/riv/aktivita	N S
http://linked.open...avai/riv/aktivity	N, S
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Staněk, Libor
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Všeobecná fakultní nemocnice v Praze / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	233088
http://linked.open...ai/riv/idVysledku	RIV/00064165:_____/11:10991
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	myocardium; ischemia; reperfusion; free radical; uncoupling protein (en)
http://linked.open.../riv/klicoveSlovo	ischemia myocardium reperfusion free radical uncoupling protein
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[DDB575C7ACA5]
http://linked.open...i/riv/nazevZdroje	Scientia Agriculturae Bohemica
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	42
http://linked.open...iv/tvurceVysledku	Fučíková, A. Lísová, Soňa Staněk, Libor
issn	1211-3174
number of pages	6 (xsd:int)

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