About: Production of Clinical Grade Mesenchymal Stromal Cells

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.intechopen.com/articles/show/title/production-of-clinical-grade-mesenchymal-stromal-cells
Description	Mesenchymal stromal cells (MSC, MSCs) are cells firstly described 35 years ago in bone marrow but present basically in all adult and fetal tissues, where they reside in the vessel wall as part of the population of pericytes. In the vessel wall as part of the population of pericytes. These rare cells (10-6-10-4 of nucleated cells in various tissues received special attention of biomedical researchers as they are easy to expand and able to differentiate in various cell and tissue types. Later, these cells were found to be little immunogenic and to have immunosuppressive properties, which they exert by action on T cells, B cells, NK cells and dendritic cells ... Mesenchymal stromal cells (MSC, MSCs) are cells firstly described 35 years ago in bone marrow but present basically in all adult and fetal tissues, where they reside in the vessel wall as part of the population of pericytes. In the vessel wall as part of the population of pericytes. These rare cells (10-6-10-4 of nucleated cells in various tissues received special attention of biomedical researchers as they are easy to expand and able to differentiate in various cell and tissue types. Later, these cells were found to be little immunogenic and to have immunosuppressive properties, which they exert by action on T cells, B cells, NK cells and dendritic cells ... (en)
Title	Production of Clinical Grade Mesenchymal Stromal Cells Production of Clinical Grade Mesenchymal Stromal Cells (en)
skos:prefLabel	Production of Clinical Grade Mesenchymal Stromal Cells Production of Clinical Grade Mesenchymal Stromal Cells (en)
skos:notation	RIV/00064165:_____/11:10643!RIV12-MZ0-00064165
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MSM0021620808)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Pytlík, Robert Slanař, Ondřej
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Všeobecná fakultní nemocnice v Praze / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	224265
http://linked.open...ai/riv/idVysledku	RIV/00064165:_____/11:10643
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Mesenchymal stromal cells (MSC, MSCs); GMP preparation; airborne particulate cleanliness.; autologous / allogeneic material; bone marrow mononuclear cells; Trophoblastic tissues; placental MSCs; monoclonal antibodies; cultivation medium; research-grade media DMEM; fetal calf serum; allergic reactions; xenogeneic protein; serum-free media; autologous human plasma; cytokine-suplemented medium; antibiotics; Harvesting of adherent cells; cryopreservation; viability; clonogenicity; senescence; Donor screening; Microbial contamination; Mycoplasma; Endotoxin testing; Tumorigenicity (en)
http://linked.open.../riv/klicoveSlovo	viability Donor screening Endotoxin testing GMP preparation Harvesting of adherent cells MSCs) Mesenchymal stromal cells (MSC Microbial contamination Mycoplasma Trophoblastic tissues Tumorigenicity airborne particulate cleanliness. allergic reactions autologous / allogeneic material autologous human plasma bone marrow mononuclear cells clonogenicity cultivation medium cytokine-suplemented medium placental MSCs research-grade media DMEM serum-free media xenogeneic protein antibiotics cryopreservation senescence fetal calf serum monoclonal antibodies
http://linked.open...ontrolniKodProRIV	[31CB18A8A505]
http://linked.open...i/riv/mistoVydani	Rijeka, Croatia
http://linked.open...i/riv/nazevZdroje	Regenerative Medicine and Tissue Engineering - Cells and Biomaterials
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...v/pocetStranKnihy	588 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Pytlík, Robert Stehlík, David Matějková, E. Slanař, Ondřej
http://linked.open...n/vavai/riv/zamer	Molekulárně biologické, genetické a epigenetické aspekty vzniku a rozvoje modelových tumorů dospělého věku. Význam pro epidemiologii, časnou diagnostiku a léčbu
number of pages	34 (xsd:int)
http://purl.org/ne...btex#hasPublisher	InTech
https://schema.org/isbn	978-953-307-663-8

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