About: Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders     Goto   Sponge   NotDistinct   Permalink

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  • Dopamine receptors control neural signals that modulates behavior. Dopamine plays an important role in normal attention; that is the reason for studying the genes of the dopaminergic system, mainly in connection with disorders of attention. DRD4 influences the postsynaptic action of dopamine and is implicated in many neurological processes, exhibits polymorphism and is one of the most studied genes in connection with psychiatric disorders. Associations were found with ADHD (attention deficit hyperactivity disorder), substance dependences, several specific personality traits, and reaction to stress. These findings have implications for pharmacogenetics. This article reviews the principle published associations of DRD4 variants with psychiatric disorders.
  • Dopamine receptors control neural signals that modulates behavior. Dopamine plays an important role in normal attention; that is the reason for studying the genes of the dopaminergic system, mainly in connection with disorders of attention. DRD4 influences the postsynaptic action of dopamine and is implicated in many neurological processes, exhibits polymorphism and is one of the most studied genes in connection with psychiatric disorders. Associations were found with ADHD (attention deficit hyperactivity disorder), substance dependences, several specific personality traits, and reaction to stress. These findings have implications for pharmacogenetics. This article reviews the principle published associations of DRD4 variants with psychiatric disorders. (en)
Title
  • Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders
  • Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders (en)
skos:prefLabel
  • Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders
  • Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders (en)
skos:notation
  • RIV/00064165:_____/11:#0000016!RIV12-MPS-00064165
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(HC 202/2010), V
http://linked.open...iv/cisloPeriodika
  • 17
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 195304
http://linked.open...ai/riv/idVysledku
  • RIV/00064165:_____/11:#0000016
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • psychopathology; genetics; dopamine (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [EF71CCF365C1]
http://linked.open...i/riv/nazevZdroje
  • Medical Science Monitor
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 2011
http://linked.open...iv/tvurceVysledku
  • Kuželová, Hana
  • Ptáček, Radek
  • Stefano, George B.
issn
  • 1643-3750
number of pages
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