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  • Left ventricular hypertrophy is the hallmark of cardiac involvement in Fabry disease. However the pathophysiology of Fabry disease-related cardiomyopathy is still poorly understood.In our study we have demonstrated, based on magnetic resosonance spectroscopy and repeated echocardiographic examinations, a positive correlation between cardiac energy metabolism status at the time of diagnosis of Fabry disease and gain of left ventricular mass during several years of follow-up. Impaired cardiac energy metabolism, ether primary or secondary, probably plays important role in the pathogenesis of left ventricular hypertrophy in Fabry disease.
  • Left ventricular hypertrophy is the hallmark of cardiac involvement in Fabry disease. However the pathophysiology of Fabry disease-related cardiomyopathy is still poorly understood.In our study we have demonstrated, based on magnetic resosonance spectroscopy and repeated echocardiographic examinations, a positive correlation between cardiac energy metabolism status at the time of diagnosis of Fabry disease and gain of left ventricular mass during several years of follow-up. Impaired cardiac energy metabolism, ether primary or secondary, probably plays important role in the pathogenesis of left ventricular hypertrophy in Fabry disease. (en)
Title
  • Association between cardiac energy metabolism and gain of left ventricular mass in Fabry disease
  • Association between cardiac energy metabolism and gain of left ventricular mass in Fabry disease (en)
skos:prefLabel
  • Association between cardiac energy metabolism and gain of left ventricular mass in Fabry disease
  • Association between cardiac energy metabolism and gain of left ventricular mass in Fabry disease (en)
skos:notation
  • RIV/00064165:_____/10:7884!RIV11-MZ0-00064165
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(1M0510), Z(MSM0021620817)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
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  • 247949
http://linked.open...ai/riv/idVysledku
  • RIV/00064165:_____/10:7884
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  • Fabry disease; Cardiomyopathy; Echocardiography; Magnetic resonance spectroscopy; Myocardial energy metabolism; magnetic-resonance spectroscopy; hypertrophic cardiomyopathy; dilated cardiomyopathy; manifestations; storage; heart (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • IE - Irsko
http://linked.open...ontrolniKodProRIV
  • [AE518C823B20]
http://linked.open...i/riv/nazevZdroje
  • International Journal of Cardiology
http://linked.open...in/vavai/riv/obor
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  • 144
http://linked.open...iv/tvurceVysledku
  • Bultas, Jan
  • Elleder, Milan
  • Kautzner, Josef
  • Karetová, Debora
  • Linhart, Aleš
  • Paleček, Tomáš
  • Hájek, Milan
  • Kuchynka, Petr
http://linked.open...ain/vavai/riv/wos
  • 000282678300071
http://linked.open...n/vavai/riv/zamer
issn
  • 0167-5273
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