About: Clinical presentation and metabolic consequences in 40 breastfed infants with nutritional vitamin B-12 deficiency - What have we learned?     Goto   Sponge   NotDistinct   Permalink

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  • Maternal vitamin B12 (Cbl) deficiency causes nutritional Cbl deficiency in breastfed infants. Insufficient absorption due to chronic gastritis was the major cause of maternal Cbl deficiency in this series. In these, usually asymptomatic mothers, a routine oral Cbl supplementation in pregnancy and lactation is insufficient. Clinical presentation of severe deficiency was typical, consisting of failure to thrive, hypotonia, developmental delay/regression, microcephaly and megaloblastic anaemia. The best prevention in future could be the screening of all pregnant women.
  • Maternal vitamin B12 (Cbl) deficiency causes nutritional Cbl deficiency in breastfed infants. Insufficient absorption due to chronic gastritis was the major cause of maternal Cbl deficiency in this series. In these, usually asymptomatic mothers, a routine oral Cbl supplementation in pregnancy and lactation is insufficient. Clinical presentation of severe deficiency was typical, consisting of failure to thrive, hypotonia, developmental delay/regression, microcephaly and megaloblastic anaemia. The best prevention in future could be the screening of all pregnant women. (en)
Title
  • Clinical presentation and metabolic consequences in 40 breastfed infants with nutritional vitamin B-12 deficiency - What have we learned?
  • Clinical presentation and metabolic consequences in 40 breastfed infants with nutritional vitamin B-12 deficiency - What have we learned? (en)
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  • Clinical presentation and metabolic consequences in 40 breastfed infants with nutritional vitamin B-12 deficiency - What have we learned?
  • Clinical presentation and metabolic consequences in 40 breastfed infants with nutritional vitamin B-12 deficiency - What have we learned? (en)
skos:notation
  • RIV/00064165:_____/10:6857!RIV11-MZ0-00064165
http://linked.open...avai/riv/aktivita
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  • I, Z(MSM0021620806), Z(MSM0021620849)
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  • 6
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  • 250962
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  • RIV/00064165:_____/10:6857
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  • Vitamin B-12 deficiency; Breastfeeding; Failure to thrive; Hypotonia; Developmental delay; Methylmalonic aciduria; Hyperhomocysteinemia (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [933B4EBE3679]
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  • European Journal of Paediatric Neurology
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  • 14
http://linked.open...iv/tvurceVysledku
  • Smolka, Vratislav
  • Honzík, Tomáš
  • Magner, Martin
  • Zeman, Jiří
  • Adamovičová, Miriam
  • Hrubá, Eva
http://linked.open...ain/vavai/riv/wos
  • 000284570200004
http://linked.open...n/vavai/riv/zamer
issn
  • 1090-3798
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