About: Western blot analysis for the detection of serum antibodies recognizing linear Aquaporin-4 epitopes in patients with Neuromyelitis Optica     Goto   Sponge   NotDistinct   Permalink

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  • This paper presents a western blot assay showing good sensitivity (81%) and specificity (97%) for detecting serum antibodies to Aquaporin-4 (AQP4) in patients with Neuromyelitis Optica (NMO). By using western blot, we were able to distinguish serum immunoreactivity against either of the two AQP4 isoforms, showing that antibodies recognizing the linear AQP4-M1 isoform are specific for NMO.
  • This paper presents a western blot assay showing good sensitivity (81%) and specificity (97%) for detecting serum antibodies to Aquaporin-4 (AQP4) in patients with Neuromyelitis Optica (NMO). By using western blot, we were able to distinguish serum immunoreactivity against either of the two AQP4 isoforms, showing that antibodies recognizing the linear AQP4-M1 isoform are specific for NMO. (en)
Title
  • Western blot analysis for the detection of serum antibodies recognizing linear Aquaporin-4 epitopes in patients with Neuromyelitis Optica
  • Western blot analysis for the detection of serum antibodies recognizing linear Aquaporin-4 epitopes in patients with Neuromyelitis Optica (en)
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  • Western blot analysis for the detection of serum antibodies recognizing linear Aquaporin-4 epitopes in patients with Neuromyelitis Optica
  • Western blot analysis for the detection of serum antibodies recognizing linear Aquaporin-4 epitopes in patients with Neuromyelitis Optica (en)
skos:notation
  • RIV/00064165:_____/09:5964!RIV10-MZ0-00064165
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  • 1-2
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  • 351857
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  • RIV/00064165:_____/09:5964
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  • Aquaporin-4; Neuromyelitis Optica; AQP-4 antibodies; multiple-sclerosis; water channel; anti-aquaporin-4 antibody; diagnostic-criteria; arrays; marker; assay; igg; nmo (en)
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  • NL - Nizozemsko
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  • [50108EC7BFDF]
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  • Journal of Neuroimmunology
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  • 217
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  • Nytrová, Petra
  • Bertolotto, Antonio
  • Marnetto, Fabiana
  • Capobianco, Marco
  • Frau, Jessica
  • Gilli, Francesca
  • Granieri, Letizia
  • Hellias, Bianca
  • Patanella, Agata Katia
  • Sala, Arianna
http://linked.open...ain/vavai/riv/wos
  • 000272896700013
issn
  • 0165-5728
number of pages
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