About: Natriuretic peptides - physiology, pathophysiology and clinical use in heart failure

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Natriuretic peptides (NPs) are synthesised and released by myocardium in response to increased cardiac wall stress. Plasma levels of NPs increase early in congestive heart failure, to lesser degree also in other clinical situations, e.g. acute coronary syndroms and pulmonary embolism. According to results of many clinical trials, NPs become valuable tools for diagnosing heart failure. Plasma levels of NPs are also independant predictors of prognosis. They are related to both, cardiovascular morbidity and mortality. Several clinical studies indicate that treatment of heart failure guided by BNP and NT-proBNP levels could improve clinical outcomes. Natriuretic peptides (NPs) are synthesised and released by myocardium in response to increased cardiac wall stress. Plasma levels of NPs increase early in congestive heart failure, to lesser degree also in other clinical situations, e.g. acute coronary syndroms and pulmonary embolism. According to results of many clinical trials, NPs become valuable tools for diagnosing heart failure. Plasma levels of NPs are also independant predictors of prognosis. They are related to both, cardiovascular morbidity and mortality. Several clinical studies indicate that treatment of heart failure guided by BNP and NT-proBNP levels could improve clinical outcomes. (en)
Title	Natriuretic peptides - physiology, pathophysiology and clinical use in heart failure Natriuretic peptides - physiology, pathophysiology and clinical use in heart failure (en)
skos:prefLabel	Natriuretic peptides - physiology, pathophysiology and clinical use in heart failure Natriuretic peptides - physiology, pathophysiology and clinical use in heart failure (en)
skos:notation	RIV/00064165:_____/09:4811!RIV10-MZ0-00064165
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Janota, Tomáš Hradec, Jaromír Krupičková, Zdislava Krupička, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Všeobecná fakultní nemocnice v Praze / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	328607
http://linked.open...ai/riv/idVysledku	RIV/00064165:_____/09:4811
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Heart failure diagnosis; heart failure treatment; natriuretic peptides; BNP; NT-proBNP; OPTIMA study; left-ventricular dysfunction; nt-probnp; emergency diagnosis; molecular-biology; renal-function; brain; bnp; atrial; impact; performance (en)
http://linked.open.../riv/klicoveSlovo	BNP molecular-biology NT-proBNP impact natriuretic peptides performance atrial left-ventricular dysfunction brain renal-function Heart failure diagnosis OPTIMA study bnp emergency diagnosis heart failure treatment nt-probnp
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[68B554F118CF]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	58
http://linked.open...iv/tvurceVysledku	Hradec, Jaromír Janota, Tomáš Krupička, Jan Kasalová, Zdislava
http://linked.open...ain/vavai/riv/wos	000265853100002
issn	0862-8408
number of pages	7 (xsd:int)

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