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  • We present a case report of intoxication by a potentially lethal dose of sustained-release verapamil with delayed escalation of complications. The patient was hospitalized 1.5 h after an attempted suicide with a very high dose of verapamil sustained-release (72 g). On admission the plasma concentrations were extremely high (3600 ng/l). Heart rate and blood pressure declined slowly with a surprising sudden escalation on the third day coupled with hemodynamic collapse and loss of consciousness. Complete recovery was achieved in spite of 2 h of extreme hypotension. We outline the clinical course, a need for massive bowel irrigation in case of sustained-release medication, the timing of a temporary pacing and the effect of centralization of circulation even on invasively measured blood pressure. European Journal of Emergency Medicine 16:100-102 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
  • We present a case report of intoxication by a potentially lethal dose of sustained-release verapamil with delayed escalation of complications. The patient was hospitalized 1.5 h after an attempted suicide with a very high dose of verapamil sustained-release (72 g). On admission the plasma concentrations were extremely high (3600 ng/l). Heart rate and blood pressure declined slowly with a surprising sudden escalation on the third day coupled with hemodynamic collapse and loss of consciousness. Complete recovery was achieved in spite of 2 h of extreme hypotension. We outline the clinical course, a need for massive bowel irrigation in case of sustained-release medication, the timing of a temporary pacing and the effect of centralization of circulation even on invasively measured blood pressure. European Journal of Emergency Medicine 16:100-102 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins. (en)
Title
  • Surprisingly delayed escalation of severe verapamil poisoning
  • Surprisingly delayed escalation of severe verapamil poisoning (en)
skos:prefLabel
  • Surprisingly delayed escalation of severe verapamil poisoning
  • Surprisingly delayed escalation of severe verapamil poisoning (en)
skos:notation
  • RIV/00064165:_____/09:4019!RIV10-MZ0-00064165
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 344819
http://linked.open...ai/riv/idVysledku
  • RIV/00064165:_____/09:4019
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Cardiac pacing; intoxication; shock; verapamil; release verapamil; overdose; intoxication (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [74DC5B948D40]
http://linked.open...i/riv/nazevZdroje
  • European Journal of Emergency Medicine
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 16
http://linked.open...iv/tvurceVysledku
  • Kotrlíková, Eva
  • Malík, Jan
  • Tuka, Vladimír
  • Janota, Jan
  • Říčařová, Bronislava
http://linked.open...ain/vavai/riv/wos
  • 000264516800009
issn
  • 0969-9546
number of pages
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