About: Immune Response of Chicken Gut to Natural Colonization by Gut Microflora and to Salmonella enterica Serovar Enteritidis Infection

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this work we were interested in the development of the gut microbial community, the immune response to natural microbial colonization, and the response to Salmonella Enteritidis infection as a function of chicken age. The complexity of chicken gut microbiota gradually increased from day 1 to day 19 of life. For the first 3 days of life, chicken cecum showed increased expression of chicken beta-defensins, and then dropped. On the other hand, an increase in IL-8 and IL-17 expression was observed in chicken cecum on day 4 of life, indicating physiological inflammation and maturation of the gut immune system. In agreement, the response of chickens infected with S. Enteritidis on days 1, 4, and 16 of life shifted from Th1 (induction of IFN-gamma and iNOS), observed in younger chickens, to Th17, observed in 16-day-old chickens (induction of IL-17). Active modification of chicken gut microbiota in the future may influence the maturation of the gut immune system and increase its resistance to infection. In this work we were interested in the development of the gut microbial community, the immune response to natural microbial colonization, and the response to Salmonella Enteritidis infection as a function of chicken age. The complexity of chicken gut microbiota gradually increased from day 1 to day 19 of life. For the first 3 days of life, chicken cecum showed increased expression of chicken beta-defensins, and then dropped. On the other hand, an increase in IL-8 and IL-17 expression was observed in chicken cecum on day 4 of life, indicating physiological inflammation and maturation of the gut immune system. In agreement, the response of chickens infected with S. Enteritidis on days 1, 4, and 16 of life shifted from Th1 (induction of IFN-gamma and iNOS), observed in younger chickens, to Th17, observed in 16-day-old chickens (induction of IL-17). Active modification of chicken gut microbiota in the future may influence the maturation of the gut immune system and increase its resistance to infection. (en)
Title	Immune Response of Chicken Gut to Natural Colonization by Gut Microflora and to Salmonella enterica Serovar Enteritidis Infection Immune Response of Chicken Gut to Natural Colonization by Gut Microflora and to Salmonella enterica Serovar Enteritidis Infection (en)
skos:prefLabel	Immune Response of Chicken Gut to Natural Colonization by Gut Microflora and to Salmonella enterica Serovar Enteritidis Infection Immune Response of Chicken Gut to Natural Colonization by Gut Microflora and to Salmonella enterica Serovar Enteritidis Infection (en)
skos:notation	RIV/00027162:_____/11:#0000777!RIV12-MZE-00027162
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ED0006/01/01), P(QH91238), Z(MZE0002716202)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Hradecká, Helena Havlíčková, Hana Crhánová, Magdaléna Matulová, Marta Rychlík, Ivan Šišák, František Faldynová, Marcela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	203598
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/11:#0000777
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	COMPETITIVE-EXCLUSION; POSTNATAL-DEVELOPMENT; SEROTYPE TYPHIMURIUM; INTERNAL CONTROL; INNATE IMMUNITY; LAMINA PROPRIA; EXPRESSION; INTESTINE; IL-22; CELLS (en)
http://linked.open.../riv/klicoveSlovo	CELLS INNATE IMMUNITY EXPRESSION COMPETITIVE-EXCLUSION IL-22 INTERNAL CONTROL INTESTINE LAMINA PROPRIA POSTNATAL-DEVELOPMENT SEROTYPE TYPHIMURIUM
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[FDC7CFC8DFD7]
http://linked.open...i/riv/nazevZdroje	Infection and Immunity
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Advanced Microbiology & Immunology Research in Veterinary Medicine Vaccination and protection of poultry against Salmonella infection
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	79
http://linked.open...iv/tvurceVysledku	Crhánová, Magdaléna Havlíčková, Hana Hradecká, Helena Matulová, Marta Rychlík, Ivan Šišák, František Faldynová, Marcela
http://linked.open...ain/vavai/riv/wos	000291788700027
http://linked.open...n/vavai/riv/zamer	Animal disease research, prevention and food chain protection
issn	0019-9567
number of pages	9 (xsd:int)

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