About: Usefulness of detection of specific IgM and IgG antibodies for diagnosis of clinical encephalitozoonosis in pet rabbits

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About: Usefulness of detection of specific IgM and IgG antibodies for diagnosis of clinical encephalitozoonosis in pet rabbits Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Encephalitozoon cuniculi is an obligate intracellular pathogen that has wide host distribution, but primary affects rabbits. This study presents a seroepidemiological study of E. cuniculi infection in 500 pet rabbits from the Czech Republic using ELISA capable of measuring IgM and IgG antibodies. Specific IgM antibodies, reflecting acute or reactivate infection, were detected in 32.4% of all rabbits. IgG antibodies indicating exposure to infection, were presented in 68.0% of all rabbits. Presence of IgM antibodies is indicative for active infection with requirement to institute proper antimicrosporidial therapy. As active infection was detected in considerably high numbers of rabbits with clinical signs that are not usually associated with E. cuniculi, and even in asymptomatic rabbits, detection of both isotypes of specific antibodies should be a routine part of a health check in rabbits. Encephalitozoon cuniculi is an obligate intracellular pathogen that has wide host distribution, but primary affects rabbits. This study presents a seroepidemiological study of E. cuniculi infection in 500 pet rabbits from the Czech Republic using ELISA capable of measuring IgM and IgG antibodies. Specific IgM antibodies, reflecting acute or reactivate infection, were detected in 32.4% of all rabbits. IgG antibodies indicating exposure to infection, were presented in 68.0% of all rabbits. Presence of IgM antibodies is indicative for active infection with requirement to institute proper antimicrosporidial therapy. As active infection was detected in considerably high numbers of rabbits with clinical signs that are not usually associated with E. cuniculi, and even in asymptomatic rabbits, detection of both isotypes of specific antibodies should be a routine part of a health check in rabbits. (en)
Title	Usefulness of detection of specific IgM and IgG antibodies for diagnosis of clinical encephalitozoonosis in pet rabbits Usefulness of detection of specific IgM and IgG antibodies for diagnosis of clinical encephalitozoonosis in pet rabbits (en)
skos:prefLabel	Usefulness of detection of specific IgM and IgG antibodies for diagnosis of clinical encephalitozoonosis in pet rabbits Usefulness of detection of specific IgM and IgG antibodies for diagnosis of clinical encephalitozoonosis in pet rabbits (en)
skos:notation	RIV/00027162:_____/10:#0000623!RIV11-GA0-00027162
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GP524/08/P568), S, Z(MSM6215712402)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Faldyna, Martin Kovařčík, Kamil Jeklová, Edita
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	294751
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/10:#0000623
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Encephalitozoon cuniculi; Rabbit; ELISA; Serology; Toxoplasma gondii; Neurological disorders (en)
http://linked.open.../riv/klicoveSlovo	ELISA Encephalitozoon cuniculi Rabbit Toxoplasma gondii Serology Neurological disorders
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[F5BE3822CD21]
http://linked.open...i/riv/nazevZdroje	Veterinary Parasitology
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Immune response of rabbits (Oryctolagus cuniculus) to experimental infection with Encephalitozoon cuniculi
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	170
http://linked.open...iv/tvurceVysledku	Faldyna, Martin Hauptman, K. Jekl, V. Jeklová, Edita Knotek, Z. Koudela, B. Kovařčík, Kamil Neumayerová, H.
http://linked.open...ain/vavai/riv/wos	000278678500021
http://linked.open...n/vavai/riv/zamer	Veterinary aspects of food safety and quality
issn	0304-4017
number of pages	6 (xsd:int)

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