About: Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages

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About: Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this study we were interested in the serovars which are frequently isolated from pigs i.e. S. Typhimurium, S. Derby and S. Infantis with porcine pulmonary macrophages. Four hours post addition of bacteria to PAMs, higher numbers of intracellular S. Typhimurium than S. Derby or S. Infantis were observed. However within next 24 hours, counts of S. Typhimurium did not change while S. Derby and S. Infantis increased their counts 10 and 5 times, respectively. The apparent inability of S. Typhimurium to multiply inside PAMs was caused by its higher cytotoxicity. The IL-1beta, IL-8, IL-12p40, IL-23p19 and TNFalpha response to S. Derby and S. Infantis was always higher than to S. Typhimurium. The lower cytokine signaling but higher cytotoxicity of S. Typhimurium for macrophages correlates with the higher virulence for pigs of this serotype when compared with S. Derby or S. Infantis. In this study we were interested in the serovars which are frequently isolated from pigs i.e. S. Typhimurium, S. Derby and S. Infantis with porcine pulmonary macrophages. Four hours post addition of bacteria to PAMs, higher numbers of intracellular S. Typhimurium than S. Derby or S. Infantis were observed. However within next 24 hours, counts of S. Typhimurium did not change while S. Derby and S. Infantis increased their counts 10 and 5 times, respectively. The apparent inability of S. Typhimurium to multiply inside PAMs was caused by its higher cytotoxicity. The IL-1beta, IL-8, IL-12p40, IL-23p19 and TNFalpha response to S. Derby and S. Infantis was always higher than to S. Typhimurium. The lower cytokine signaling but higher cytotoxicity of S. Typhimurium for macrophages correlates with the higher virulence for pigs of this serotype when compared with S. Derby or S. Infantis. (en)
Title	Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages (en)
skos:prefLabel	Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages (en)
skos:notation	RIV/00027162:_____/10:#0000621!RIV11-MZE-00027162
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ED0006/01/01), P(QH81062), Z(MZE0002716202)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Hradecká, Helena Faldyna, Martin Matiašovic, Ján Volf, Jiří Ondráčková, Petra Havlíčková, Hana Rychlík, Ivan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	257392
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/10:#0000621
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Derby; Infantis; Typhimurium; pig; macrophage (en)
http://linked.open.../riv/klicoveSlovo	macrophage Typhimurium pig Derby Infantis
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[754540F029FF]
http://linked.open...i/riv/nazevZdroje	Veterinary Microbiology
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Immunology and immunodiagnostics of salmonella infection in pig Center for Advanced Microbiology & Immunology Research in Veterinary Medicine
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	140
http://linked.open...iv/tvurceVysledku	Faldyna, Martin Havlíčková, Hana Hradecká, Helena Matiašovic, Ján Rychlík, Ivan Volf, Jiří Ondráčková, Petra
http://linked.open...ain/vavai/riv/wos	000284664800014
http://linked.open...n/vavai/riv/zamer	Animal disease research, prevention and food chain protection
issn	0378-1135
number of pages	6 (xsd:int)

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