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  • The objectives of this study were established to investigate the whole chromosome set of in vivo obtained early pig embryos, applying methods of whole genome amplification and comparative genomic hybridization (CGH). 11 (14.3%) of the 77 pig embryos examined, were observed to be aneuploid. We found chromosome errors comprising loss/gain of one or few chromosomes (10.4%) but also extensive chromosome imbalances (3.9%). Chromosomes 8, 11, 12, 13, 17, and X were most frequently involved in aneuploidies, when compared to chromosomes 2, 9, and 18, which were rarely involved in chromosome errors.
  • The objectives of this study were established to investigate the whole chromosome set of in vivo obtained early pig embryos, applying methods of whole genome amplification and comparative genomic hybridization (CGH). 11 (14.3%) of the 77 pig embryos examined, were observed to be aneuploid. We found chromosome errors comprising loss/gain of one or few chromosomes (10.4%) but also extensive chromosome imbalances (3.9%). Chromosomes 8, 11, 12, 13, 17, and X were most frequently involved in aneuploidies, when compared to chromosomes 2, 9, and 18, which were rarely involved in chromosome errors. (en)
Title
  • Investigation of Chromosome Aneuploidies in Early Porcine Embryos Using Comparative Genomic Hybridization
  • Investigation of Chromosome Aneuploidies in Early Porcine Embryos Using Comparative Genomic Hybridization (en)
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  • Investigation of Chromosome Aneuploidies in Early Porcine Embryos Using Comparative Genomic Hybridization
  • Investigation of Chromosome Aneuploidies in Early Porcine Embryos Using Comparative Genomic Hybridization (en)
skos:notation
  • RIV/00027162:_____/09:#0000564!RIV10-MZE-00027162
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  • P(QH81068)
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  • 1-2
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  • 320301
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  • RIV/00027162:_____/09:#0000564
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  • whole genome amplification; comparative genomic hybridization; pig; embryo; aneuploidy (en)
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  • CH - Švýcarská konfederace
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  • [8DD1138F23E2]
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  • Cytogenetic and Genome Research
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  • 126
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  • Kubíčková, Svatava
  • Rubeš, Jiří
  • Hulínská, Pavlína
  • Musilová, Petra
  • Horňák, Miroslav
http://linked.open...ain/vavai/riv/wos
  • 000272605100022
issn
  • 1424-8581
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