| Attributes | Values |
|---|
| rdf:type
| |
| Description
| - Totally, 400 aphidicolin-induced breakages were analyzed from eight young and clinically healthy animals of river buffalo (Bubalus bubalis, 2n = 50) with the aim of establishing a 'fragile site map' of the species.In the river buffalo karyotype, 51 fragile sites were detected and localized on the standardized ideogram of the species. The most fragile bands were as follows: 9q213 with 24 breakages out of 400; 19q21 with 16, 17q21 and inacXq24 with 15, 15q23 with 13 and 13q23 with 12 breaks, respectively. Previous gene mapping analysis in this species has revealed that the closest loci to these fragile sites contain genes such as RASA1 and CAST (9q214), NPR3 and C9 (19q19), PLP and BTK (Xq24-q25), OarCP09 (15q24), and EDNRB (13q22) whose mutations are responsible for severe phenotypic malformations and immunodeficiency in humans as well as in mice and meat quality in pigs.
- Totally, 400 aphidicolin-induced breakages were analyzed from eight young and clinically healthy animals of river buffalo (Bubalus bubalis, 2n = 50) with the aim of establishing a 'fragile site map' of the species.In the river buffalo karyotype, 51 fragile sites were detected and localized on the standardized ideogram of the species. The most fragile bands were as follows: 9q213 with 24 breakages out of 400; 19q21 with 16, 17q21 and inacXq24 with 15, 15q23 with 13 and 13q23 with 12 breaks, respectively. Previous gene mapping analysis in this species has revealed that the closest loci to these fragile sites contain genes such as RASA1 and CAST (9q214), NPR3 and C9 (19q19), PLP and BTK (Xq24-q25), OarCP09 (15q24), and EDNRB (13q22) whose mutations are responsible for severe phenotypic malformations and immunodeficiency in humans as well as in mice and meat quality in pigs. (en)
- Celkem 400 aphidicolinem-indukovanách zlomů bylo analyzováno u osmi mladých, klinicky zdravých jedinců buvola (Bubalus bubalis, 2n = 50) s cílem stanovit mapu fragilních míst u tohoto druhu. Na karyotypu bylo detekováno a lokalizováno 51 fragilních míst. Nejvíce fragilní pruhy byly: 9q213 s 24 zlomy ze 400; 19q21 s 16, 17q21 a inacXq24 s 15, 15q23 s 13 a 13q23 s 12 zlomy. Předchozí mapování genů u tohoto druhu odhalilo, že nejbližší lokusy k těmto fragilním místům obsahují geny, jako jsou RASA1 a CAST (9q214), NPR3 a C9 (19q19), PLP a BTK (Xq24-q25), OarCP09 (15q24), a EDNRB (13q22), jejichž mutace jsou zodpovědné za vážné fenotypické malformace a imunodeficienci u lidí a myší a kvalitu masu u prasat. (cs)
|
| Title
| - Chromosomal expression and localization of aphidicolin-induced fragile sites in the standard karyotype of river buffalo (Bubalus bubalis)
- Chromozomální exprese a lokalizace aphidicolinem-indukovaných fragilních míst na standardním karyotypu buvola (Bubalus bubalis) (cs)
- Chromosomal expression and localization of aphidicolin-induced fragile sites in the standard karyotype of river buffalo (Bubalus bubalis) (en)
|
| skos:prefLabel
| - Chromosomal expression and localization of aphidicolin-induced fragile sites in the standard karyotype of river buffalo (Bubalus bubalis)
- Chromozomální exprese a lokalizace aphidicolinem-indukovaných fragilních míst na standardním karyotypu buvola (Bubalus bubalis) (cs)
- Chromosomal expression and localization of aphidicolin-induced fragile sites in the standard karyotype of river buffalo (Bubalus bubalis) (en)
|
| skos:notation
| - RIV/00027162:_____/08:#0000425!RIV09-MZE-00027162
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| |
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/00027162:_____/08:#0000425
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - aphidicolin; fragile site; Bubalus bubalis (en)
|
| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - CH - Švýcarská konfederace
|
| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - Cytogenetic and Genome Research
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Rubeš, Jiří
- Cosenza, G.
- Di Berardino, D.
- Iannuzzi, L.
- Peretti, V.
- Ramunno, L.
- Coppola, G.
- Nicodemo, D.
- Pauciullo, A.
- Ciotola, F.
- Di Meo, G.
|
| http://linked.open...ain/vavai/riv/wos
| |
| http://linked.open...n/vavai/riv/zamer
| |
| issn
| |
| number of pages
| |
![[RDF Data]](/fct/images/sw-rdf-blue.png)
![[cxml]](/fct/images/cxml_doc.png)
![[csv]](/fct/images/csv_doc.png)
![[text]](/fct/images/ntriples_doc.png)
![[turtle]](/fct/images/n3turtle_doc.png)
![[ld+json]](/fct/images/jsonld_doc.png)
![[rdf+json]](/fct/images/json_doc.png)
![[rdf+xml]](/fct/images/xml_doc.png)
![[atom+xml]](/fct/images/atom_doc.png)
![[html]](/fct/images/html_doc.png)