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Description
  • Termín abnormality spermií byl původně vztahován zejména k morfologii spermií. S novými metodami užívanými k monitorování genetického poškození u lidí, jako je fluorescenční in situ hybridizace a stanovení poruch chromatinu ve spermiích, byly získány výsledky důležité jak pro veřejné zdraví, tak pro klinickou praxi. V práci jsou shrnuty data o vlivu profesionální expozice a životního stylu na poškození spermií. Pokles procenta morfologicky normálních spermií a nárůst DNA fragmentace spermií stejně jako aneuploidií chromozomů ve spermiích mají negativní vliv na reprodukci. (cs)
  • The impact of sperm abnormalities for humans became a hot topic due to its possible effect on male fertility. Also the term “sperm abnormality” was originally related to the sperm morphology and the sperm head morphology. With new methods used for the human monitoring of genetic damage as fluorescent in situ hybridization and sperm chromatin structure assay were obtained results important to public health and clinical practice. Present data on occupational exposure, life style, and biomarkers of sperm injury are reviewed. As the air pollution substantially improved, semen parameters improved, too. The determination of sperm morphology, DNA fragmentation by SCSA, and sperm aneuploidy may be recommended as sensitive biomarkers. An observed decrease of percentage of normal sperm morphology and increase of DNA fragmentation by SCSA and sperm aneuploidy may have adverse effects on reproductive outcomes.
  • The impact of sperm abnormalities for humans became a hot topic due to its possible effect on male fertility. Also the term “sperm abnormality” was originally related to the sperm morphology and the sperm head morphology. With new methods used for the human monitoring of genetic damage as fluorescent in situ hybridization and sperm chromatin structure assay were obtained results important to public health and clinical practice. Present data on occupational exposure, life style, and biomarkers of sperm injury are reviewed. As the air pollution substantially improved, semen parameters improved, too. The determination of sperm morphology, DNA fragmentation by SCSA, and sperm aneuploidy may be recommended as sensitive biomarkers. An observed decrease of percentage of normal sperm morphology and increase of DNA fragmentation by SCSA and sperm aneuploidy may have adverse effects on reproductive outcomes. (en)
Title
  • Sperm Abnormalities in Exposed Humans
  • Abnormality spermií u exponovaných mužů (cs)
  • Sperm Abnormalities in Exposed Humans (en)
skos:prefLabel
  • Sperm Abnormalities in Exposed Humans
  • Abnormality spermií u exponovaných mužů (cs)
  • Sperm Abnormalities in Exposed Humans (en)
skos:notation
  • RIV/00027162:_____/07:#0000296!RIV08-MZE-00027162
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MZE0002716201)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 451608
http://linked.open...ai/riv/idVysledku
  • RIV/00027162:_____/07:#0000296
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • air pollution; sperm quality; sperm morphology; sperm DNA damage; sperm aneuploidy (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [3FADD4243B88]
http://linked.open...i/riv/mistoVydani
  • Cambridge, UK
http://linked.open...i/riv/nazevZdroje
  • Sperm Abnormalities in Exposed Humans
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Rubeš, Jiří
  • Šrám, R.
http://linked.open...n/vavai/riv/zamer
number of pages
http://purl.org/ne...btex#hasPublisher
  • Royal Society of Chemistry
https://schema.org/isbn
  • 978-0-85404-847-2
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