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| rdf:type
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| Description
| - Cílem studie bylo rozšířit poznatky o postnatálním vývoji imunitního systému králíka ze dvou pohledů. Prvním aspektem byla aktivovatelnost lymfocytů z krve, sleziny, mesenteriální a popliteální mízní uzliny po stimulaci mitogenem Concanavalin A. Druhým aspektem byly změny ve schopnosti produkovat protilátky proti tetanovému toxoidu v průběhu maturace. Proliferační schopnost lymfocytů byla v porovnání s dospělými králíky snížená v mesenteriální mízní uzlině u novorozenců, v krvi do věku 2 týdnů a v popliteální uzlině do věku 4 týdnů. Vysoká spontánní proliferace přetrvávající do věku 2 týdnů byla nalezena ve slezině. Studium protilátkové odpovědi ukázalo, že i jednodenní králíci jsou schopni tvorby specifických protilátek isotypu IgM i IgG. Nicméně, intenzita a také začátek jejich tvorby byl u jednodenních a 2 a 4 týdny starých králíků nižší než u dospělých králíků. (cs)
- The aim of study was to extend knowledge concerning development of the immune system in rabbits from two aspects. Firstly, capability of lymphocytes from blood, spleen, and lymph nodes to respond to Concanavalin A stimulation was investigated. Secondly, changes in the ability to produce antibodies against tetanus toxoid by rabbits during maturation were studied. Proliferation of lymphocytes was reduced in mesenteric lymph nodes in newborns, in blood up to the age of 2 weeks, and in popliteal lymph nodes up to the age of 4 weeks when compared to adults. High spontaneous lymphocyte proliferation that lasted up to the age of 2 weeks was recorded in spleen. The study of antibody response showed that even one-day-old rabbits were able to form specific antibodies of isotype IgM and IgG. Nevertheless, lower formation of both isotypes was noted in one-day and 2-week-old rabbits, and commencement of IgG isotype formation was delayed in one day, 2-week, and 4-week-old rabbits when compared to adults.
- The aim of study was to extend knowledge concerning development of the immune system in rabbits from two aspects. Firstly, capability of lymphocytes from blood, spleen, and lymph nodes to respond to Concanavalin A stimulation was investigated. Secondly, changes in the ability to produce antibodies against tetanus toxoid by rabbits during maturation were studied. Proliferation of lymphocytes was reduced in mesenteric lymph nodes in newborns, in blood up to the age of 2 weeks, and in popliteal lymph nodes up to the age of 4 weeks when compared to adults. High spontaneous lymphocyte proliferation that lasted up to the age of 2 weeks was recorded in spleen. The study of antibody response showed that even one-day-old rabbits were able to form specific antibodies of isotype IgM and IgG. Nevertheless, lower formation of both isotypes was noted in one-day and 2-week-old rabbits, and commencement of IgG isotype formation was delayed in one day, 2-week, and 4-week-old rabbits when compared to adults. (en)
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| Title
| - Functional development of immune response in rabbits
- Funkční vývoj imunitního systému u králíků (cs)
- Functional development of immune response in rabbits (en)
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| skos:prefLabel
| - Functional development of immune response in rabbits
- Funkční vývoj imunitního systému u králíků (cs)
- Functional development of immune response in rabbits (en)
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| skos:notation
| - RIV/00027162:_____/07:#0000215!RIV08-MZE-00027162
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00027162:_____/07:#0000215
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Canine; Skin; Lymphocyte subsets; Lymphocyte activity; Immunocomplexes (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Veterinary Immunology and Immunopathology
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Faldyna, Martin
- Levá, Lenka
- Jeklová, Edita
- Kudláčková, Hana
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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