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| rdf:type
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| Description
| - Chromosomes of fourteen captive-born mountain reedbucks (Redunca fulvorufula) have been investigated. Chromosomal complement was 2n=56 (FN=60). The mountain reedbuck karyotype consists of two biarmed pairs resulting from two centric fusions involving chromosomes 2;25 and 6;10, respectively. In some animals, 57 chromosomes were detected. Variation in the diploid number was the result of polymorphism for the 6;10 centric fusion. Both X and Y chromosomes are large and acrocentric. The Y chromosome and the proximal part of the X chromosome appeared to stain entirely heterochromatic. The chromosomes X, 9 and 14 appeared to be of caprine type. Chromosomal aberrations have been detected in two of the 14 animals investigated. The de novo formed Robertsonian translocation 56,XX,rob(6;13) was found in one female heterozygote for the fusion 6;10. The double heterozygote was sharing monobrachial homology for chromosome 6.
- Chromosomes of fourteen captive-born mountain reedbucks (Redunca fulvorufula) have been investigated. Chromosomal complement was 2n=56 (FN=60). The mountain reedbuck karyotype consists of two biarmed pairs resulting from two centric fusions involving chromosomes 2;25 and 6;10, respectively. In some animals, 57 chromosomes were detected. Variation in the diploid number was the result of polymorphism for the 6;10 centric fusion. Both X and Y chromosomes are large and acrocentric. The Y chromosome and the proximal part of the X chromosome appeared to stain entirely heterochromatic. The chromosomes X, 9 and 14 appeared to be of caprine type. Chromosomal aberrations have been detected in two of the 14 animals investigated. The de novo formed Robertsonian translocation 56,XX,rob(6;13) was found in one female heterozygote for the fusion 6;10. The double heterozygote was sharing monobrachial homology for chromosome 6. (en)
- Sledovali jsme vliv postnatální expozice benzo(a)pyrenu (BaP) na vývoj dělohy, expresi estrogenového receptoru alfa (ER alfa) a na odpověď dělohy na stimulaci estrogenem za použití uterotrofní bioeseje u potkanů. Novorozencům byl každý den po dobu 14 dní s.c. aplikován BaP nebo ethynylestradiol nebo vehikulum (kontrolní skupina). Potkani byli zabiti ve stáří 23 dnů. Postnatální aplikace BaP v dávkách 1.0 a 10.0 mg/kg způsobila redukci váhy dělohy a snížení exprese ER alfa v luminálním epitelu. Zvýšení váhy dělohy a výšky luminálního epitelu po EE stimulaci ve 20-22 dni stáří bylo vyšší u všech skupin ve srovnání se skupinou nestimulovanou. Nicméně, uterotrofní odpověď potkanů postnatálně exponovaných EE a BaP byla nižší než u kontrol. Studie ukázala, že postnatální expozice BaP vyvolává změny v konstituci a maturaci ER alfa v děloze, což následně vede k narušenému vývoji a funkci dělohy u imaturních potkanů. (cs)
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| Title
| - Effect of postnatal exposure to benzo(a)pyrene on the uterus of immature rats
- Effect of postnatal exposure to benzo(a)pyrene on the uterus of immature rats (en)
- Vliv postnatální expozice benzo(a)pyrenu na dělohu nematurovaných potkanů (cs)
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| skos:prefLabel
| - Effect of postnatal exposure to benzo(a)pyrene on the uterus of immature rats
- Effect of postnatal exposure to benzo(a)pyrene on the uterus of immature rats (en)
- Vliv postnatální expozice benzo(a)pyrenu na dělohu nematurovaných potkanů (cs)
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| skos:notation
| - RIV/00027162:_____/07:#0000196!RIV08-MZE-00027162
|
| http://linked.open.../vavai/riv/strany
| |
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(GA525/05/2695), Z(MZE0002716201)
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| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/00027162:_____/07:#0000196
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - endocrine disruptors; estradiol; estrogen receptor alpha; immunohistochemistry; polycyclic aromatic hydrocarbons; rat uterotrophy bioassay; reproductive system (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
|
| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - Experimental and Toxicologic Pathology
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Faldyna, Martin
- Matiašovic, Ján
- Zralý, Zdeněk
- Kummer, Vladimír
- Mašková, Jarmila
|
| http://linked.open...n/vavai/riv/zamer
| |
| issn
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| number of pages
| |
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