About: The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid

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About: The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cílem studie bylo posoudit intenzitu protilátkové odpovědi selat s deficitem železa. Skupina deseti selat nebyla suplementována žádným preparátem až do věku 21 dní. Deset selat ve druhé skupině bylo ve věku 3 dnů intramuskulárně suplementováno 200 mg Fe3+ vázaného na dextran. Všechna selata byla ve věku 14 dnů imunizována tetanovým toxoidem. Reimunizace byla provedena 21 dní později. U nesuplementovaných selat se rozvinula anémie detekovatelná pomocí hematologických ukazatelů a stanovením koncentrace železa v plasmě. Titr specifických protilátek izotypu IgM a IgG byl detekován v týdenních intervalech pomocí ELISA. Dynamika protilátkové odpovědi byla podobná u obou skupin selat a nebyl prokázán žádný statisticky významný rozdíl mezi skupinami v žádném termínu experimentu. (cs) The aim of this study was to investigate an antibody response to tetanus toxoid in iron-deficient piglets. Ten piglets were not given any iron preparation until the age of 21 days. Ten piglets were given 200 mg Fe3+ dextran intramuscularly at the age of 3 days. All piglets were immunized with tetanus toxoid 14 days after birth. Reimmunization was performed 21 days after the first immunization. IgM and IgG titres were measured in weekly intervals after immunization. Haematological indices and iron concentration in the blood plasma of iron-deficient piglets characterized iron deficiency. The dynamic changes in IgM and IgG response to tetanus toxoid were similar in iron-deficient and iron-supplemented piglets and no significant differences in titres between the two groups were found in any period of the trial. The aim of this study was to investigate an antibody response to tetanus toxoid in iron-deficient piglets. Ten piglets were not given any iron preparation until the age of 21 days. Ten piglets were given 200 mg Fe3+ dextran intramuscularly at the age of 3 days. All piglets were immunized with tetanus toxoid 14 days after birth. Reimmunization was performed 21 days after the first immunization. IgM and IgG titres were measured in weekly intervals after immunization. Haematological indices and iron concentration in the blood plasma of iron-deficient piglets characterized iron deficiency. The dynamic changes in IgM and IgG response to tetanus toxoid were similar in iron-deficient and iron-supplemented piglets and no significant differences in titres between the two groups were found in any period of the trial. (en)
Title	The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid (en) Nedostatek železa u selat nemá negativní vliv na protilátkovou odpověď na aplikovaný tetanový toxoid. (cs)
skos:prefLabel	The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid (en) Nedostatek železa u selat nemá negativní vliv na protilátkovou odpověď na aplikovaný tetanový toxoid. (cs)
skos:notation	RIV/00027162:_____/07:#0000180!RIV08-MZE-00027162
http://linked.open.../vavai/riv/strany	179;185
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1B44024), Z(MSM6215712403)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Nechvátalová, Kateřina Faldyna, Martin Krejčí, Josef
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	408326
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/07:#0000180
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	piglets; iron; antibodies; immunity; tetanus toxoid (en)
http://linked.open.../riv/klicoveSlovo	antibodies tetanus toxoid piglets iron immunity
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[F6444DB5ADDB]
http://linked.open...i/riv/nazevZdroje	Veterinární medicína
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Methods of the efficiency improvement of vaccination procedures in farm animals.
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	52
http://linked.open...iv/tvurceVysledku	Faldyna, Martin Nechvátalová, Kateřina Svoboda, M. Krejčí, Josef Ficek, R. Drábek, J.
http://linked.open...n/vavai/riv/zamer	Active creation of health, yield and performance of the large animals
issn	0375-8427
number of pages	7 (xsd:int)

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