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  • This work characterises macrophage morphological features during initiation and resolution of the inflammatory response by the bovine mammary gland. The study has been carried out in 20 mammary glands of 5 virgin heifers by using light microscopy of natural and stained cells and by using transmissive electron microscopy (TEM). The inflammatory reaction was induced by an intramammary administration of PBS. It has been found that both the initial as well as the resolution phases of the inflammatory reaction are characteristic of the presence of various morphologically different macrophage forms. During the initial phase of the inflammatory response, the major proportion of the macrophage population consisted of monocyte like macrophages, which represented newly migrated cells. Morphologically different forms of macrophages reflected their real time functions in the inflammation process.
  • This work characterises macrophage morphological features during initiation and resolution of the inflammatory response by the bovine mammary gland. The study has been carried out in 20 mammary glands of 5 virgin heifers by using light microscopy of natural and stained cells and by using transmissive electron microscopy (TEM). The inflammatory reaction was induced by an intramammary administration of PBS. It has been found that both the initial as well as the resolution phases of the inflammatory reaction are characteristic of the presence of various morphologically different macrophage forms. During the initial phase of the inflammatory response, the major proportion of the macrophage population consisted of monocyte like macrophages, which represented newly migrated cells. Morphologically different forms of macrophages reflected their real time functions in the inflammation process. (en)
  • V této práci byly charakterizovány morfologické vlastnosti makrofágů v průběhu iniciace a rezoluce zánětlivé odpovědi mléčné žlázy skotu. Studie byla provedena na 20 mléčných žlázách 5 virginních jalovic s použitím světelné mikroskopie nativních a barvených buněk a pomocí transmisní elektronové mikroskopie (TEM). Zánětlivá reakce mléčné žlázy byla indukována intramammární instilaci PBS. Bylo zjištěno, že obě fáze zánětlivé reakce -- iniciální fáze a fáze rezoluce - jsou charakteristické přítomností různých morfologicky diferentních forem makrofágů. Během iniciální fáze zánětlivé odpovědi tvořily majoritní podíl populace makrofágů monocytům podobné makrofágy, jež představovaly čerstvě migrované buňky. Morfologicky diferentních formy makrofágů odrážely jejich aktuální funkci v průběhu zánětu. (cs)
Title
  • Macrophages of the bovine heifer mammary gland: morphological features during initiation and resolution of the inflammatory response
  • Macrophages of the bovine heifer mammary gland: morphological features during initiation and resolution of the inflammatory response (en)
  • Makrofágy v mléčných žlázách jalovic: morfologické rysy během počáteční a rozlišovací fáze imunitní odpovědi. (cs)
skos:prefLabel
  • Macrophages of the bovine heifer mammary gland: morphological features during initiation and resolution of the inflammatory response
  • Macrophages of the bovine heifer mammary gland: morphological features during initiation and resolution of the inflammatory response (en)
  • Makrofágy v mléčných žlázách jalovic: morfologické rysy během počáteční a rozlišovací fáze imunitní odpovědi. (cs)
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  • RIV/00027162:_____/06:#0000057!RIV07-MZE-00027162
http://linked.open.../vavai/riv/strany
  • 2
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA524/03/1531), Z(MZE0002716201)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 483812
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  • RIV/00027162:_____/06:#0000057
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  • macrophages, mammary gland (en)
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  • DE - Spolková republika Německo
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  • [B7A8DF2703FE]
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  • Anatomia Histologia Embryologia
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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  • Sládek, Zbyšek
http://linked.open...n/vavai/riv/zamer
issn
  • 0340-2096
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