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| rdf:type
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| Description
| - M.caprae vyvolává tuberkulózu mezi zvířaty a ojediněle mezi lidmi v některých Evopských státech. K popisu M.caprae jsme analyzovali 232 M caprae izolátů pomocí MIRU a spoligotypingu. Izoláty pocházely ze 128 vzdálených lokalit z 10 zemí. Objevili jsem 78různých MIRU typů, ale pouze 17 spoligotypů, které vytvářely Hunter-Gaston diskriminační indexy 0.941 (MIRU) a 0.665 (spoligotyping). V podskupině 103 M.caprae izolátů pocházející z ohnisek byly srovnávány výsledky získané MIRU a IS6110 RFLP, kteréposkytly podobný diskriminační výsledek. MIRU lokusy 4, 26, a 31 nejvíce odlišovaly M.caprae; následovaly lokusy 10 a 16, jejichž kombinace je jiná než ta, která je uváděna jako nejlepší pro M.bovis. MIRU typy M.caprae společně s publikovanými údaji bylypoužity pro analýzu Neighbor-joining method. M.caprae izoláty vytvářeny jednu skupinu s příbuznými klasickými zástupci MTC, mimo stály %22moderní%22 M.tuberculosis. Námi získaná data potvrdila, že M.caprae je odlišná fylogenetická %22rodina%22 uvnitř MTC. (cs)
- M.caprae causes tuberculosis among animals and humans in several European countries. To characterize M.caprae we analyzed 232 M caprae isolates by MIRU and by spoligotyping. The isolates originated from 128 epidemiological settings in 10 countries. Wefound 78 different MIRU types but only 17 spoligotypes, giving Hunter-Gaston discriminatory indices of 0.941 (MIRU) and 0.665 (spoligotyping). For a subset of 103 M.caprae isolates derived from outbreaks, MIRU and IS6110 RFLP were compared and shown toprovide similar results. MIRU loci 4, 26, and 31 were most discriminant in M.caprae, followed by loci 10 and 16, a combination which is different than those reported to discriminate M.bovis best. M.caprae MIRU patterns together with published data wereused for the neighbor-joining method. M.caprae isolates were grouped together, closely related to the branches of classical members MTC, but apart from modern M.tuberculosis. Our data confirm M.caprae as a distinct phylogenetic lineage within the MTC.
- M.caprae causes tuberculosis among animals and humans in several European countries. To characterize M.caprae we analyzed 232 M caprae isolates by MIRU and by spoligotyping. The isolates originated from 128 epidemiological settings in 10 countries. Wefound 78 different MIRU types but only 17 spoligotypes, giving Hunter-Gaston discriminatory indices of 0.941 (MIRU) and 0.665 (spoligotyping). For a subset of 103 M.caprae isolates derived from outbreaks, MIRU and IS6110 RFLP were compared and shown toprovide similar results. MIRU loci 4, 26, and 31 were most discriminant in M.caprae, followed by loci 10 and 16, a combination which is different than those reported to discriminate M.bovis best. M.caprae MIRU patterns together with published data wereused for the neighbor-joining method. M.caprae isolates were grouped together, closely related to the branches of classical members MTC, but apart from modern M.tuberculosis. Our data confirm M.caprae as a distinct phylogenetic lineage within the MTC. (en)
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| Title
| - Characterization of Mycobacterium caprae by mycobacterial interspersed repetitive units (MIRU) for epidemiological and phylogenetic purposes
- Characterization of Mycobacterium caprae by mycobacterial interspersed repetitive units (MIRU) for epidemiological and phylogenetic purposes (en)
- Charakteristika izolátů Mycobacterium caprae získaných v Evropě pomocí metody MIRU (mycobacterial interspersed repetitive unit) genotyping (cs)
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| skos:prefLabel
| - Characterization of Mycobacterium caprae by mycobacterial interspersed repetitive units (MIRU) for epidemiological and phylogenetic purposes
- Characterization of Mycobacterium caprae by mycobacterial interspersed repetitive units (MIRU) for epidemiological and phylogenetic purposes (en)
- Charakteristika izolátů Mycobacterium caprae získaných v Evropě pomocí metody MIRU (mycobacterial interspersed repetitive unit) genotyping (cs)
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| skos:notation
| - RIV/00027162:_____/05:06000045!RIV06-MZE-00027162
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00027162:_____/05:06000045
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - fragment-length-polymorphism; tuberculosis complex; molecular epidemiology; genetic diversity; tandem repeats; cattle; strains; differentiation (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Journal of Clinical Microbiology
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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