About: Individual variation in the frequency of sperm aneuploidy in humans

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Individual variation in the frequency of sperm aneuploidy in humans Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To examine interindividual differences in sperm chromosome aneuploidy, repeated semen specimens were obtained from a group of ten healthy men, aged 20-21 at the start of the study, and analyzed by FISH to determine the frequencies of sperm aneuploidy forchromosomes X, Y, 8, 18 and 21 and of diploidy. Men were sampled three times over a 5-year period. Statistical analysis examining the stability of sperm aneuploidy over time by type and chromosome identified two men who consistently exhibited elevatedfrequencies of sperm aneuploidy. Overall, disomy frequencies were lower for chromosome X, 8 and 18 than for chromosomes 21 or Y and for XY aneuploidy. The frequency of chromosome Y disomy did not differ from XY sperm frequency. Frequencies of spermaneuploidy were similar between the first sampling period and the second, two years later. However, the frequency of some types of aneuploidy increased significantly between the first sampling period and the last, five years later. To examine interindividual differences in sperm chromosome aneuploidy, repeated semen specimens were obtained from a group of ten healthy men, aged 20-21 at the start of the study, and analyzed by FISH to determine the frequencies of sperm aneuploidy forchromosomes X, Y, 8, 18 and 21 and of diploidy. Men were sampled three times over a 5-year period. Statistical analysis examining the stability of sperm aneuploidy over time by type and chromosome identified two men who consistently exhibited elevatedfrequencies of sperm aneuploidy. Overall, disomy frequencies were lower for chromosome X, 8 and 18 than for chromosomes 21 or Y and for XY aneuploidy. The frequency of chromosome Y disomy did not differ from XY sperm frequency. Frequencies of spermaneuploidy were similar between the first sampling period and the second, two years later. However, the frequency of some types of aneuploidy increased significantly between the first sampling period and the last, five years later. (en) Spermie 10 mladých mužů byly vyšetřeny třikrát v průběhu pěti let na frekvenci aneuploidií chromozomů pomocí FISH. Byla popsána vysoká interindividuální variabilita ve frekvenci aneuploidií chromozomů ve spermiích, které mohou u některých jedinců vyvolatzvýšené riziko narození vývojové vady a embryonální mortality. U některých typů aneuploidií došlo k zvýšení frekvence mezi prvním a posledním vyšetření, tedy s věkem. (cs)
Title	Individual variation in the frequency of sperm aneuploidy in humans Individual variation in the frequency of sperm aneuploidy in humans (en) Individuální variace ve frekvenci aneuploidií v lidských spermiích (cs)
skos:prefLabel	Individual variation in the frequency of sperm aneuploidy in humans Individual variation in the frequency of sperm aneuploidy in humans (en) Individuální variace ve frekvenci aneuploidií v lidských spermiích (cs)
skos:notation	RIV/00027162:_____/05:06000026!RIV06-MZE-00027162
http://linked.open.../vavai/riv/strany	229;236
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MZE0002716201)
http://linked.open...iv/cisloPeriodika	3-4
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Rubeš, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	524573
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/05:06000026
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Human sperm aneuploidy; FISH; Chromosomes X, Y, 8, 18, 21 (en)
http://linked.open.../riv/klicoveSlovo	Y 18 FISH 8 Chromosomes X Human sperm aneuploidy 21
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[24108625E8DC]
http://linked.open...i/riv/nazevZdroje	Cytogenetic and Genome Research
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	111
http://linked.open...iv/tvurceVysledku	Rubeš, Jiří
http://linked.open...n/vavai/riv/zamer	Zdravá zvířata a bezpečné potraviny jako základ pro zdraví lidí
issn	1424-8581
number of pages	8 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software