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| Description
| - We compared the differences in clinical, radiological, pathological changes and cytological findings in blood and bronchoalveolar lavage (BAL) samples between groups of piglets, with different types and levels of antigen-specific immunity afterActinobacillus pleuropneumoniae (App) challenge.Piglets that obtained colostrum-derived antibodies and experienced a low-dose App infection were best protected against App challenge.More apparent clinical and pathol.changes were observed in groupsprotected with either only colostrum-derived antibodies or active immunity induced by a preceding low-dose infection.However, none of the types of protection prevented developing of the disease and characteristic changes in the lungs.Cell counts changesin blood and BAL gave evidence of only bacterial infection in progress; however, between-group differences were not marked.Antibodies (IgG, IgA) present in the respir.tract at the time of challenge played a major role in protection against App infection
- We compared the differences in clinical, radiological, pathological changes and cytological findings in blood and bronchoalveolar lavage (BAL) samples between groups of piglets, with different types and levels of antigen-specific immunity afterActinobacillus pleuropneumoniae (App) challenge.Piglets that obtained colostrum-derived antibodies and experienced a low-dose App infection were best protected against App challenge.More apparent clinical and pathol.changes were observed in groupsprotected with either only colostrum-derived antibodies or active immunity induced by a preceding low-dose infection.However, none of the types of protection prevented developing of the disease and characteristic changes in the lungs.Cell counts changesin blood and BAL gave evidence of only bacterial infection in progress; however, between-group differences were not marked.Antibodies (IgG, IgA) present in the respir.tract at the time of challenge played a major role in protection against App infection (en)
- Studie porovnává u selat s rozdílným typem a úrovní antigen-specifické imunity rozdíly v klinických, radiologických, patologických a cytologických nálezech v periferní krvi a bronchoalveolárních lavážích (BAL) po čelenži Actinobacillus pleuropneumoniae(App). Nejlépe chráněna byla při čelenži ta selata, která přijala kolostrem antigen-specifické protilátky a současně prodělala slabou infekci. Výraznější klinické a patologické změny byly zaznamenány u selat chráněných pouze kolostrálními protilátkaminebopouze aktivní imunitou indukovanou předchozí slabou infekcí. Žádný z typů imunity ovšem nezabránil rozvoji infekce a vzniku typických změn na plicích. Změny v zastoupení jednotlivých buněk v krvi a BAL vypovídaly pouze o probíhající bakteriálníinfekci, ale bez meziskupinovaných rozdílů. Zásadní roli při obraně proti App hrály antigen-specifické protilátky (IgG, IgA) přítomné v respiračním traktu. (cs)
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| Title
| - Significance of different types and levels of antigen-specific immunity to Actinobacillus pleuropneumoniae infection in piglets
- Význam rozdílných typů a úrovní antigen-specifické imunity selat při infekci Actinobacillus pleuropneumoniae (cs)
- Significance of different types and levels of antigen-specific immunity to Actinobacillus pleuropneumoniae infection in piglets (en)
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| skos:prefLabel
| - Significance of different types and levels of antigen-specific immunity to Actinobacillus pleuropneumoniae infection in piglets
- Význam rozdílných typů a úrovní antigen-specifické imunity selat při infekci Actinobacillus pleuropneumoniae (cs)
- Significance of different types and levels of antigen-specific immunity to Actinobacillus pleuropneumoniae infection in piglets (en)
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| skos:notation
| - RIV/00027162:_____/05:06000023!RIV06-MZE-00027162
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(GA524/01/0290), Z(MZE0002716201)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00027162:_____/05:06000023
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Bacterial infection; Bronchoalveolar lavage; Mucosal immunity; Pneumonia; Porcine; Protection; Respiratory tract (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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