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| rdf:type
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| Description
| - The aim of this study was to investigate the effect of neonatal iron deficiency on immune functions in young piglets. While control piglets were not given any iron preparation until the age of 21 days, another group of piglets was given 200 mg of Fe(3+)-dextran i.m. on day 3. Red blood cell parameters in the former, iron-deficient group were characteristic of hypochromic anaemia. In addition, the total leucocyte count (P < 0.01), relative and absolute neutrophil count (P < 0.01) and absolute lymphocyte count (P < 0.05) in peripheral blood were found significantly lower in iron-deficient piglets than in their iron-supplemented counterparts. Lymphocyte activity as measured by in vitro lymphocyte transformation test was impaired in iron-deficient piglets. A statistically significant decrease in circulating B-lymphocyte numbers was found in non-supplemented animals. Iron deficiency apparently negatively influenced the immunocompetence in piglets.
- The aim of this study was to investigate the effect of neonatal iron deficiency on immune functions in young piglets. While control piglets were not given any iron preparation until the age of 21 days, another group of piglets was given 200 mg of Fe(3+)-dextran i.m. on day 3. Red blood cell parameters in the former, iron-deficient group were characteristic of hypochromic anaemia. In addition, the total leucocyte count (P < 0.01), relative and absolute neutrophil count (P < 0.01) and absolute lymphocyte count (P < 0.05) in peripheral blood were found significantly lower in iron-deficient piglets than in their iron-supplemented counterparts. Lymphocyte activity as measured by in vitro lymphocyte transformation test was impaired in iron-deficient piglets. A statistically significant decrease in circulating B-lymphocyte numbers was found in non-supplemented animals. Iron deficiency apparently negatively influenced the immunocompetence in piglets. (en)
- Cílem studie bylo popsat efekt nedostatku železa v postnatální fázi života selat na funkci jejich imunitního systému. Zatímco jedna skupina selat nedostala žádný preparát s železem do věku 21 dní, druhá skupina selat dostala 3.den života intramuskulárně 200 mg dextranu železa. Parametry červené krevní řady u selat s nedostatkem železa byly charakteristické pro hypochromní anémii. Celkový počet leukocytů (P < 0,01), relativní a celkový počet neutrofilních granulocytů (P < 0.01) a celkový počet lymfocytů (P < 0,05) byl v krvi těchto selat signifikantně nižší než u selat železem suplementovaných. U selat s nedostatkem železa byla dále detekována snížená aktivita lymfocytů měřená in vitro testem lymfocytární transformace a statisticky signifikantně snížený počet cirkulujících B lymfocytů. Nedostatek železa měl zjevný negativní dopad na kompetentnost imunitního systému selat. (cs)
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| Title
| - Impairment of the peripheral lymphoid compartment in iron-deficient piglets
- Narušení funkce lymfocytů u selat s nedostatkem železa (cs)
- Impairment of the peripheral lymphoid compartment in iron-deficient piglets (en)
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| skos:prefLabel
| - Impairment of the peripheral lymphoid compartment in iron-deficient piglets
- Narušení funkce lymfocytů u selat s nedostatkem železa (cs)
- Impairment of the peripheral lymphoid compartment in iron-deficient piglets (en)
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| skos:notation
| - RIV/00027162:_____/04:00013632!RIV/2005/GA0/M03005/N
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(GA523/03/0186), Z(MSM 161700002)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00027162:_____/04:00013632
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - anemia;iron;piglet;immunity;immunosuppression (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Journal of Veterinary Medicine B
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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