About: New glutathione formulation for sustained release from gastrointestinal tract Asian Congress on Biotechnology (Poster. Asian Congress on Biotechnology 2013. December 15-19, 2013. Dilli, India).

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About: New glutathione formulation for sustained release from gastrointestinal tract Asian Congress on Biotechnology (Poster. Asian Congress on Biotechnology 2013. December 15-19, 2013. Dilli, India). Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To improve glutathione bioavailability after oral administration we have incorporated it into microparticles of ethylcellulose and/or cellulose acetate phthalate. Commercial FMC’s Aquacoat® EC (ethylcellulose) and Aquacoat® CPD (cellulose acetate phthalate) pseudo-latex preparations have been used for the microparticles production. FMC’s Aquacoat® pseudo-latex technology enables aqueous presentation of water-insoluble polymers. These reliable aqueous functional coatings are designed for use in both pharmaceutical and nutritional solid dose applications. They provide desired modified release profiles with the added benefit of global regulatory acceptance. Chitosan (medium molecular weight ) was added to the Aquacoat® pseudo-latex mixtures in amount of 5 - 10 % of DM to improve mucoadhesivity of the microparticles. Two methods of the microparticles preparation were tested and compared – conventional spray drying and the carbon dioxide assisted nebulisation. To improve glutathione bioavailability after oral administration we have incorporated it into microparticles of ethylcellulose and/or cellulose acetate phthalate. Commercial FMC’s Aquacoat® EC (ethylcellulose) and Aquacoat® CPD (cellulose acetate phthalate) pseudo-latex preparations have been used for the microparticles production. FMC’s Aquacoat® pseudo-latex technology enables aqueous presentation of water-insoluble polymers. These reliable aqueous functional coatings are designed for use in both pharmaceutical and nutritional solid dose applications. They provide desired modified release profiles with the added benefit of global regulatory acceptance. Chitosan (medium molecular weight ) was added to the Aquacoat® pseudo-latex mixtures in amount of 5 - 10 % of DM to improve mucoadhesivity of the microparticles. Two methods of the microparticles preparation were tested and compared – conventional spray drying and the carbon dioxide assisted nebulisation. (en)
Title	New glutathione formulation for sustained release from gastrointestinal tract Asian Congress on Biotechnology (Poster. Asian Congress on Biotechnology 2013. December 15-19, 2013. Dilli, India). New glutathione formulation for sustained release from gastrointestinal tract Asian Congress on Biotechnology (Poster. Asian Congress on Biotechnology 2013. December 15-19, 2013. Dilli, India). (en)
skos:prefLabel	New glutathione formulation for sustained release from gastrointestinal tract Asian Congress on Biotechnology (Poster. Asian Congress on Biotechnology 2013. December 15-19, 2013. Dilli, India). New glutathione formulation for sustained release from gastrointestinal tract Asian Congress on Biotechnology (Poster. Asian Congress on Biotechnology 2013. December 15-19, 2013. Dilli, India). (en)
skos:notation	RIV/00027022:_____/13:00000439!RIV14-MPO-00027022
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(FR-TI3/496)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Beran, Miloš Urban, Marian Adámek, Lubomír Drahorád, Josef Molík, Petr
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav potravinářský Praha, v.v.i.
http://linked.open...dnocenehoVysledku	91585
http://linked.open...ai/riv/idVysledku	RIV/00027022:_____/13:00000439
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	glutathione; sustained release; Aquacoat EC; Aquacoat CPD (en)
http://linked.open.../riv/klicoveSlovo	Aquacoat CPD Aquacoat EC sustained release glutathione
http://linked.open...ontrolniKodProRIV	[9174272F942E]
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	*Development of production technology and application forms of glutathione with high bioavailibility for the suppression of oxidative stress (radiation, chemotherapy)
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Beran, Miloš Hromádka, Róbert Šandriková, Viera Urban, Marian Adámek, Lubomír Drahorád, Josef Molík, Petr

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