About: Effect of antioestrogens on proliferation, differentiation and telomerase activity of pig granulosa cells in vitro

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Effect of antioestrogens on proliferation, differentiation and telomerase activity of pig granulosa cells in vitro Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of the work was to study the effect of oestrogen receptor (ER) inhibitors (ICI 164.384; ICI and cyclofenil; CF) on proliferation, oestradiol synthesis, aromatase expression and telomerase activity (TA) of pig granulosa cells (GC). Antioestrogens applied individually and in a combination significantly (P<0.01) decreased proliferative potential of LF-GC. Antioestrogens applied in a combination increased (P<0.05) 17-β oestradiol synthesis in small and large follicle GC. Antioestrogens applied individually and in a combination caused an increase (P<0.01) of aromatase gene expression in FSH-stimulated conditions as well as in basic conditions. Moreover, antioestrogens increased (P<0.05) TA in basic and in FSH-stimulated conditions. The results indicate the involvement of ER α and β in the control of proliferation, differentiation and telomerase activity in pig GC. Furthermore, TA does not have to be linked only to pig GC proliferation but may also be involved in the differentiation process. The aim of the work was to study the effect of oestrogen receptor (ER) inhibitors (ICI 164.384; ICI and cyclofenil; CF) on proliferation, oestradiol synthesis, aromatase expression and telomerase activity (TA) of pig granulosa cells (GC). Antioestrogens applied individually and in a combination significantly (P<0.01) decreased proliferative potential of LF-GC. Antioestrogens applied in a combination increased (P<0.05) 17-β oestradiol synthesis in small and large follicle GC. Antioestrogens applied individually and in a combination caused an increase (P<0.01) of aromatase gene expression in FSH-stimulated conditions as well as in basic conditions. Moreover, antioestrogens increased (P<0.05) TA in basic and in FSH-stimulated conditions. The results indicate the involvement of ER α and β in the control of proliferation, differentiation and telomerase activity in pig GC. Furthermore, TA does not have to be linked only to pig GC proliferation but may also be involved in the differentiation process. (en)
Title	Effect of antioestrogens on proliferation, differentiation and telomerase activity of pig granulosa cells in vitro Effect of antioestrogens on proliferation, differentiation and telomerase activity of pig granulosa cells in vitro (en)
skos:prefLabel	Effect of antioestrogens on proliferation, differentiation and telomerase activity of pig granulosa cells in vitro Effect of antioestrogens on proliferation, differentiation and telomerase activity of pig granulosa cells in vitro (en)
skos:notation	RIV/00027014:_____/10:#0001285!RIV11-GA0-00027014
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA523/05/2062), Z(MZE0002701401)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Tománek, Milan Chronowska, Ewa Kott, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav živočišné výroby, v.v.i.
http://linked.open...dnocenehoVysledku	255878
http://linked.open...ai/riv/idVysledku	RIV/00027014:_____/10:#0001285
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pig, granulosa cells, oestrogen receptor, antioestrogens, telomerase (en)
http://linked.open.../riv/klicoveSlovo	granulosa cells telomerase oestrogen receptor antioestrogens pig
http://linked.open...odStatuVydavatele	PL - Polská republika
http://linked.open...ontrolniKodProRIV	[ABF3560D560F]
http://linked.open...i/riv/nazevZdroje	Journal of Animal and Feed Sciences
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Developmental potential and molecular differentiation of pig follicular granulosa cells in vitro
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	19
http://linked.open...iv/tvurceVysledku	Chronowska, Ewa Kott, Tomáš Tománek, Milan
http://linked.open...ain/vavai/riv/wos	000286028700007
http://linked.open...n/vavai/riv/zamer	Od rostoucího oocytu k produkci embryí in vitro a embryonálním kmenovým buňkám: Vývojové modely a strategie produkce zárodečných, embryonálních a somatických buněk in vitro v kontextu s jejich využitím v programu zachování genetických živočišných zdrojů
issn	1230-1388
number of pages	13 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software