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Description
  • Článek diskutuje případnou asymetrickou reprogramaci jaderného materiálu u klonů RN8 vyprodukovaných přenosem jádra somatické buňky. Domníváme se, že změny v epi-/genotypu odrážejí nesouměrnou reprogramaci rodičovských chromosomů. Předpokládáme, že reprogramace paternálního materiálu neproběhne na odpovídající úrovni, vzhledem k jeho rezistenci k reprogramačním faktorům oocytu. (cs)
  • The article discusses the eventuality of asymmetric nuclear reprogramming in somatic cell nucleus transfer clones. We suggest that changes in the epi-/genotype observed in cloned embryos arise from unbalanced nuclear reprogramming between parental chromosomes. Thus, it is supposed that paternal reprogramming does not occur, as these chromosomes are rather resistent to oocyte reprogramming factors.
  • The article discusses the eventuality of asymmetric nuclear reprogramming in somatic cell nucleus transfer clones. We suggest that changes in the epi-/genotype observed in cloned embryos arise from unbalanced nuclear reprogramming between parental chromosomes. Thus, it is supposed that paternal reprogramming does not occur, as these chromosomes are rather resistent to oocyte reprogramming factors. (en)
Title
  • Asymmetric nuclear reprogramming in somatic cell nucfear transfer?
  • Asymetrická reprogramace jádra u klonů po přenosu jádra somatické buňky (cs)
  • Asymmetric nuclear reprogramming in somatic cell nucfear transfer? (en)
skos:prefLabel
  • Asymmetric nuclear reprogramming in somatic cell nucfear transfer?
  • Asymetrická reprogramace jádra u klonů po přenosu jádra somatické buňky (cs)
  • Asymmetric nuclear reprogramming in somatic cell nucfear transfer? (en)
skos:notation
  • RIV/00027014:_____/08:#0000794!RIV09-MZE-00027014
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MZE0002701401)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 357195
http://linked.open...ai/riv/idVysledku
  • RIV/00027014:_____/08:#0000794
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • nuclear transfer; somatic cells; reprogramming (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [337D5B8B28D3]
http://linked.open...i/riv/nazevZdroje
  • Bioessays
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 30
http://linked.open...iv/tvurceVysledku
  • Fulka, Josef
  • Loi, P.
http://linked.open...ain/vavai/riv/wos
  • 000252334600009
http://linked.open...n/vavai/riv/zamer
issn
  • 0265-9247
number of pages
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