About: Somatic cell nuclear transfer (SCNT) in mammals: The cytoplast and its reprogramming activities     Goto   Sponge   NotDistinct   Permalink

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  • The success of somatic cell nuclear transfer is still disappointingly low. Only about 3-5% of reconstructed embryos develop to term, and it is also evident that even if some clones are born they are not fully developed and healthy. These abnormalities probably result from an incomplete reprogramming of transferred nuclei. We discuss the methodological approaches used for the preparation of cytoplasts and their possible reprogramming activities.
  • The success of somatic cell nuclear transfer is still disappointingly low. Only about 3-5% of reconstructed embryos develop to term, and it is also evident that even if some clones are born they are not fully developed and healthy. These abnormalities probably result from an incomplete reprogramming of transferred nuclei. We discuss the methodological approaches used for the preparation of cytoplasts and their possible reprogramming activities. (en)
  • Úspěšnost klonování přenosem jader somatických buněk je stále velmi nízká. Jen 3-5% rekonstruovaných embryí dokončí svůj vývoj. Také je zřejmé, že i když se některé klony narodí, nejsou plně vyvinuté a zdravé. Tyto abnormality jsou pravděpodobně způsobeny neúplnou reprogramací přenesených jader. V práci diskutujeme metodické přístupy používané pro přípravu cytoplastů a jejich reprogramační aktivity. (cs)
Title
  • Somatic cell nuclear transfer (SCNT) in mammals: The cytoplast and its reprogramming activities
  • Somatic cell nuclear transfer (SCNT) in mammals: The cytoplast and its reprogramming activities (en)
  • Přenosy jader somatických buněk: cytoplast a jeho reprogramační aktivity. (cs)
skos:prefLabel
  • Somatic cell nuclear transfer (SCNT) in mammals: The cytoplast and its reprogramming activities
  • Somatic cell nuclear transfer (SCNT) in mammals: The cytoplast and its reprogramming activities (en)
  • Přenosy jader somatických buněk: cytoplast a jeho reprogramační aktivity. (cs)
skos:notation
  • RIV/00027014:_____/07:#0000376!RIV08-GA0-00027014
http://linked.open.../vavai/riv/strany
  • 93-102
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GESTE/05/E004)
http://linked.open...iv/cisloPeriodika
  • neuveden
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 450994
http://linked.open...ai/riv/idVysledku
  • RIV/00027014:_____/07:#0000376
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • nuclear transfer, mammals, cytoplast (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [219A304E0A30]
http://linked.open...i/riv/nazevZdroje
  • Advances in experimental medicine and biology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 591
http://linked.open...iv/tvurceVysledku
  • Fulka jr., Josef
  • Fulková, Helena
issn
  • 0065-2598
number of pages
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