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  • Development of simple and reproducible method for preparing a ciprofloxacin kit using a redox polymer, which would meet the rquirements for an easy and reliable technique of labeling with 99mTc and diagnostic efficiency in scintigrafic imaging of infection.Radiochemical purity is >95% for kit-labeling (pH 3.3.3-3.7). With pH 3.45, labelled ciprofloxacin shows the highest stability and radiochemical purity. The 99mTc-ciprofloxacin aomplex is stable for at last 8 h. In experimentally induced inflamthe amount of accumulated 99mT-ciprofloxacin activity is five times higer than in controls. The developed method of 99mTc-ciprofloxacin kit preparation emloys and redox polymer in a new procedure, which enables the preparation of a stable kit with a high99Tc-labeling efficiency. The labelled kit is suitable for scientific imaging of infection.
  • Development of simple and reproducible method for preparing a ciprofloxacin kit using a redox polymer, which would meet the rquirements for an easy and reliable technique of labeling with 99mTc and diagnostic efficiency in scintigrafic imaging of infection.Radiochemical purity is >95% for kit-labeling (pH 3.3.3-3.7). With pH 3.45, labelled ciprofloxacin shows the highest stability and radiochemical purity. The 99mTc-ciprofloxacin aomplex is stable for at last 8 h. In experimentally induced inflamthe amount of accumulated 99mT-ciprofloxacin activity is five times higer than in controls. The developed method of 99mTc-ciprofloxacin kit preparation emloys and redox polymer in a new procedure, which enables the preparation of a stable kit with a high99Tc-labeling efficiency. The labelled kit is suitable for scientific imaging of infection. (en)
Title
  • A new technique of 99mTc-ciprofloxacin kit preparation
  • A new technique of 99mTc-ciprofloxacin kit preparation (en)
skos:prefLabel
  • A new technique of 99mTc-ciprofloxacin kit preparation
  • A new technique of 99mTc-ciprofloxacin kit preparation (en)
skos:notation
  • RIV/00023841:_____/02:00005618!RIV/2003/MZ0/L18003/N
http://linked.open.../vavai/riv/strany
  • 224-229
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NL6071)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
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  • 637101
http://linked.open...ai/riv/idVysledku
  • RIV/00023841:_____/02:00005618
http://linked.open...riv/jazykVysledku
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  • redox polymer;99mTc-ciprofloxacin kit;biodistribution;infecton imaging (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [0FD2E37A1967]
http://linked.open...i/riv/nazevZdroje
  • Nuklearmedizin
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 41
http://linked.open...iv/tvurceVysledku
  • Komárek, Pavel
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