About: Is combinated treatment more effective than switching to monotherapy in patients with resistant depression? A retrospective study

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Objectives: The aim of this retrospective study was to compare the efficacy of combination therapy (combinations of antidepressants and various augmentations) and antidepressant monotherapy in the treatment of patients, who failed to respond at least to one previous antidepressant trial in the routine clinical practice. Methods: We reviewed chart documents of patients hospitalized at Prague Psychiatric Center for depressive disorder from June 2005 to June 2007 and finished at least 4 - weeks of new treatment. Depressive symptoms and overall clinical status were assessed using Montgomery and Åsberg Depression Rating Scale, Clinical Global Impression and Beck Depression Inventory-short form at the baseline and in the end of treatment. Results: We identified 49 inpatients (24-combined treatment, 25-monotherapy), who were suitable for analyses. Both groups were equal in baseline characteristics and in the duration of index episode treatment. The combined treatment was superior to the monotherapy swit Objectives: The aim of this retrospective study was to compare the efficacy of combination therapy (combinations of antidepressants and various augmentations) and antidepressant monotherapy in the treatment of patients, who failed to respond at least to one previous antidepressant trial in the routine clinical practice. Methods: We reviewed chart documents of patients hospitalized at Prague Psychiatric Center for depressive disorder from June 2005 to June 2007 and finished at least 4 - weeks of new treatment. Depressive symptoms and overall clinical status were assessed using Montgomery and Åsberg Depression Rating Scale, Clinical Global Impression and Beck Depression Inventory-short form at the baseline and in the end of treatment. Results: We identified 49 inpatients (24-combined treatment, 25-monotherapy), who were suitable for analyses. Both groups were equal in baseline characteristics and in the duration of index episode treatment. The combined treatment was superior to the monotherapy swit (en)
Title	Is combinated treatment more effective than switching to monotherapy in patients with resistant depression? A retrospective study Is combinated treatment more effective than switching to monotherapy in patients with resistant depression? A retrospective study (en)
skos:prefLabel	Is combinated treatment more effective than switching to monotherapy in patients with resistant depression? A retrospective study Is combinated treatment more effective than switching to monotherapy in patients with resistant depression? A retrospective study (en)
skos:notation	RIV/00023752:_____/09:00000974!RIV10-MZ0-00023752
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(NS10368), S, Z(MZ0PCP2005)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Šóš, Peter Kopeček, Miloslav Bareš, Martin Novák, Tomáš Stopková, Pavla
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Národní ústav duševního zdraví
http://linked.open...dnocenehoVysledku	320444
http://linked.open...ai/riv/idVysledku	RIV/00023752:_____/09:00000974
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	resistant depression; treatment; antidepressant monotherapy; combined treatment (en)
http://linked.open.../riv/klicoveSlovo	combined treatment antidepressant monotherapy treatment resistant depression
http://linked.open...odStatuVydavatele	SE - Švédské království
http://linked.open...ontrolniKodProRIV	[CB0717FCD937]
http://linked.open...i/riv/nazevZdroje	Neuroendocrinology Letters
http://linked.open...in/vavai/riv/obor	FL
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Prospective, randomized evaluation of efficacy of antidepressant monotherapy and antidepressant combination in the treatment of patients with resistant depression.
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	30
http://linked.open...iv/tvurceVysledku	Bareš, Martin Kopeček, Miloslav Novák, Tomáš Stopková, Pavla Šóš, Peter
http://linked.open...ain/vavai/riv/wos	000275266400008
http://linked.open...n/vavai/riv/zamer	Study of Sources f Psychiatric Morbidity , and Increasing the Effec-tiveness of the Preventative and Therapeutical methods in mental Health Care in the Czech Republic 2005?2011
issn	0172-780X
number of pages	6 (xsd:int)

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