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rdf:type
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Description
| - OBJECTIVES: Cognitive behaviour therapy (CBT) of primary insomnia is frequently combined with various pharmacological treatments, including sedative antidepressants. The present study was undertaken to evaluate the clinical efficacy of CBT singly and combined with trazodone pharmacotherapy, for primary insomnia. DESIGN AND SETTING: Randomised, comparative clinical trial, at a single academic medical centre. METHODS: Twenty outpatients (15 women, 5 men) with chronic primary insomnia were randomly assigned to CBT or CBT +100mg trazodone and treated for 8 weeks. The treatment outcome was estimated by mean changes from baseline in self-reported clinical scales, sleep continuity data and sleep architecture parameters. RESULTS: All patients perceived significant subjective sleep improvements. Sleep latency significantly shortened (p=0.03), sleep efficiency increased (p=0.004) and the total sleep time was significantly prolonged (p=0.006) after the CBT treatment in both groups. Sleep architecture showed that
- OBJECTIVES: Cognitive behaviour therapy (CBT) of primary insomnia is frequently combined with various pharmacological treatments, including sedative antidepressants. The present study was undertaken to evaluate the clinical efficacy of CBT singly and combined with trazodone pharmacotherapy, for primary insomnia. DESIGN AND SETTING: Randomised, comparative clinical trial, at a single academic medical centre. METHODS: Twenty outpatients (15 women, 5 men) with chronic primary insomnia were randomly assigned to CBT or CBT +100mg trazodone and treated for 8 weeks. The treatment outcome was estimated by mean changes from baseline in self-reported clinical scales, sleep continuity data and sleep architecture parameters. RESULTS: All patients perceived significant subjective sleep improvements. Sleep latency significantly shortened (p=0.03), sleep efficiency increased (p=0.004) and the total sleep time was significantly prolonged (p=0.006) after the CBT treatment in both groups. Sleep architecture showed that (en)
- Cílem studie bylo objektivně zhodnotit výsledky léčby trazodonem ve skupině pacientů s diagnozou chronické insomnie léčených kognitivně-behaviorální terapií (KBT). Metodika. Do studie bylo zařazeno 20 pacientů s diagnozou Neorganická nespavost F 51.0.15 žen a 5 mužů. Nespavost trvala průměrně 9,4 let, průměrný věk pacientů byl 47,4 let. 10 pacientů bylo léčeno pouze KBT. 10 pacientů bylo léčeno současně trazodonem a KBT. Před a po léčebné periodě bylo provedeno polysomnografické vyšetření. Výsledky. V celé skupině pacientů se statisticky významně zlepšují tyto spánkové parametry: celková doba spánku (p<0,006), spánkovou latence (p<0,03), spánkovou efektivita (p<0,004). Ve skupině léčené KBR+trazodonem došlo k statisticky významnému zvýšení zastoupení stadia S3+4 nonREM (p<0,04). Závěr: Kombinace KBT+trazodon zvyšuje zastoupení pomalovlnného spánku. (cs)
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Title
| - Trazodone improves the results of cognitive behaviour therapy of primary insomnia in non-depressed patients
- Efektivita trazodonu a kognitivně-behaviorální terapie v indikaci chronické insomnie (cs)
- Trazodone improves the results of cognitive behaviour therapy of primary insomnia in non-depressed patients (en)
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skos:prefLabel
| - Trazodone improves the results of cognitive behaviour therapy of primary insomnia in non-depressed patients
- Efektivita trazodonu a kognitivně-behaviorální terapie v indikaci chronické insomnie (cs)
- Trazodone improves the results of cognitive behaviour therapy of primary insomnia in non-depressed patients (en)
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skos:notation
| - RIV/00023752:_____/08:00000921!RIV09-MZ0-00023752
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - Z(MSM0021620816), Z(MZ0PCP2005)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00023752:_____/08:00000921
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - primary insomnia; cognitive behaviour therapy; antidepressants; trazodone; polysomnography; treatment outcome (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Neuroendocrinology Letters
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Brunovský, Martin
- Horáček, Jiří
- Höschl, Cyril
- Krajča, Vladimír
- Šóš, Peter
- Matoušek, Miloš
- Závěšická, Lucie
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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