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  • The aim of the study was to elaborate a method to estimate the degree of cognitive impairment in Alzheimer's disease from the EEG quantitative indicators. We examined 38 unmedicated patients with a diagnosis of Alzheimer's disease, with various stages (mild, moderate, and severe) of dementia. The EEG recordings were evaluated both visually and by means of computer analysis. The EEG spectra and coherences in 6 frequency bands were calculated in 16 EEG derivations. Among various EEG indicators, a decreasein the alpha coherence and an increase in the delta coherence was found to be most significantly correlated to the degree of dementia. Combining 6 variables from the spectrum and coherence analysis by means of the multiple regression model, a high corre lation (r = 0.87) between a set of EEG variables and the Mini-Mental State Examination score could be obtained. The results suggest that the EEG can supplement the clinical examination by providing an independent assessment of the degree of dementia. The
  • The aim of the study was to elaborate a method to estimate the degree of cognitive impairment in Alzheimer's disease from the EEG quantitative indicators. We examined 38 unmedicated patients with a diagnosis of Alzheimer's disease, with various stages (mild, moderate, and severe) of dementia. The EEG recordings were evaluated both visually and by means of computer analysis. The EEG spectra and coherences in 6 frequency bands were calculated in 16 EEG derivations. Among various EEG indicators, a decreasein the alpha coherence and an increase in the delta coherence was found to be most significantly correlated to the degree of dementia. Combining 6 variables from the spectrum and coherence analysis by means of the multiple regression model, a high corre lation (r = 0.87) between a set of EEG variables and the Mini-Mental State Examination score could be obtained. The results suggest that the EEG can supplement the clinical examination by providing an independent assessment of the degree of dementia. The (en)
Title
  • Objective assessment of the degree of dementia by means of EEG
  • Objective assessment of the degree of dementia by means of EEG (en)
skos:prefLabel
  • Objective assessment of the degree of dementia by means of EEG
  • Objective assessment of the degree of dementia by means of EEG (en)
skos:notation
  • RIV/00023752:_____/03:00000269!RIV/2004/MSM/L28004/N
http://linked.open.../vavai/riv/strany
  • 19-26
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LN00B122)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 618803
http://linked.open...ai/riv/idVysledku
  • RIV/00023752:_____/03:00000269
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Alzheimer's disease; EEG; spectrum analysis; coherence analysis; degree of dementia (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV
  • [C1ECCBEC116A]
http://linked.open...i/riv/nazevZdroje
  • Neuropsychobiology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 48
http://linked.open...iv/tvurceVysledku
  • Brunovský, Martin
  • Krajča, Vladimír
  • Červená, Kateřina
  • Matoušek, Miloš
  • Edman, A.
issn
  • 0302-282X
number of pages
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