About: Inhibition of TGF-beta signaling for the treatment of tumor metastasis and fibrotic diseases     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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Description
  • Transforming growth factor-beta is a cytokine involved in cell proliferation, apoptosis, differentiation, angiogenesis, cell adhesion, migration, extracellular matrix deposition, wound healing and immune response. TGF-beta supresses tumor growth in early phase of neoplasia, while promotes tumor progression and metastasis in later phases.Therefore, several possibilities for the disruption of TGF-beta signaling is very important in the treatment of tumor metastasis and fibrotic diseases.
  • Transforming growth factor-beta is a cytokine involved in cell proliferation, apoptosis, differentiation, angiogenesis, cell adhesion, migration, extracellular matrix deposition, wound healing and immune response. TGF-beta supresses tumor growth in early phase of neoplasia, while promotes tumor progression and metastasis in later phases.Therefore, several possibilities for the disruption of TGF-beta signaling is very important in the treatment of tumor metastasis and fibrotic diseases. (en)
Title
  • Inhibition of TGF-beta signaling for the treatment of tumor metastasis and fibrotic diseases
  • Inhibition of TGF-beta signaling for the treatment of tumor metastasis and fibrotic diseases (en)
skos:prefLabel
  • Inhibition of TGF-beta signaling for the treatment of tumor metastasis and fibrotic diseases
  • Inhibition of TGF-beta signaling for the treatment of tumor metastasis and fibrotic diseases (en)
skos:notation
  • RIV/00023736:_____/11:00009325!RIV12-MZ0-00023736
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LC06044), Z(MZ0UHKT2005)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
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  • 204848
http://linked.open...ai/riv/idVysledku
  • RIV/00023736:_____/11:00009325
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Inhibitory Smad; receptor-regulated Smads; small interfering RNA; TGF-beta monoclonal antibody; TGF-beta receptor kinase I inhibitors; TGF-beta signaling; transforming growth factor-beta (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • AE - Stát Spojené arabské emiráty
http://linked.open...ontrolniKodProRIV
  • [A6529DF00308]
http://linked.open...i/riv/nazevZdroje
  • Current Signal Transduction Therapy
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 6
http://linked.open...iv/tvurceVysledku
  • Fuchs, Ota
http://linked.open...n/vavai/riv/zamer
issn
  • 1574-3624
number of pages
http://bibframe.org/vocab/doi
  • 10.2174/157436211794109398
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