About: Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake

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About: Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	MRCK alpha is a serine/threonine kinase that can regulate actin/myosin assembly and activity. In article is reported, that MRCK alpha protein expression is regulated by iron levels, MRCKalpha colocalizes with transferrin loaded transferrin receptors and attenuation of MRCK alpha expression leads to a significant decrease in Tf-mediated iron uptake. MRCK alpha is a serine/threonine kinase that can regulate actin/myosin assembly and activity. In article is reported, that MRCK alpha protein expression is regulated by iron levels, MRCKalpha colocalizes with transferrin loaded transferrin receptors and attenuation of MRCK alpha expression leads to a significant decrease in Tf-mediated iron uptake. (en)
Title	Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake (en)
skos:prefLabel	Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake (en)
skos:notation	RIV/00023736:_____/10:00008646!RIV11-GA0-00023736
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0506), P(GA204/07/0830), P(GA305/09/1390), P(LC06044), P(NS10300), Z(MSM0021620806), Z(MSM0021620858), Z(MZ0UHKT2005)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Ptáčková, Pavlína Vyoral, Daniel Petrák, Jiří Čmejla, Radek
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav hematologie a krevní transfúze
http://linked.open...dnocenehoVysledku	262334
http://linked.open...ai/riv/idVysledku	RIV/00023736:_____/10:00008646
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	MRCKalpha; iron (en)
http://linked.open.../riv/klicoveSlovo	iron MRCKalpha
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[DC4E2B5932A3]
http://linked.open...i/riv/nazevZdroje	Biochemical and Biophysical Research Communications.
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Center of Molecular and Cellular Immunology Center for Experimental Hematology Therapeutic and diagnostic potential of hepcidin. Investigation of metabolic mechanisms of heart failure progression in an experimental model Iron metabolism and cellular cytoskeleton: defining a new role for MRCK?
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	395
http://linked.open...iv/tvurceVysledku	Petrák, Jiří Vyoral, Daniel Černý, J. Šebesta, O. Čmejla, Radek Ptáčková, Pavlína Savvulidi, F.
http://linked.open...ain/vavai/riv/wos	000277681000001
http://linked.open...n/vavai/riv/zamer	Molekulární biologie a patologie buňky za normy a u vybraných klinicky závažných patologických procesů Signaling and cellular response mechanisms Význam molekulárně biologických vyšetření pro objasnění patogeneze a pro diagnostiku poruch krvetvorby a využití krvetvorné buňky v léčbě onemocnění krvetvorby a jiných tkání.
issn	0006-291X
number of pages	5 (xsd:int)

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