About: Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia

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About: Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Telomere length was evaluated by terminal repeat fragment method in 66 previously untreated patients with B-chronic lymphocytic leukemia (B-CLL) to ascertain whether telomere shortening was associated with genomic aberrations, immunoglobulin variable heavy chain (IgVH) mutational status, CD38 and ZAP-70 expression, and telomerase activity. Telomere length and telomerase activity in combination with other prognostic parameters complete the risk profile of B-CLL patients and might serve for an easy decision on optimal treatment strategy. Telomere length was evaluated by terminal repeat fragment method in 66 previously untreated patients with B-chronic lymphocytic leukemia (B-CLL) to ascertain whether telomere shortening was associated with genomic aberrations, immunoglobulin variable heavy chain (IgVH) mutational status, CD38 and ZAP-70 expression, and telomerase activity. Telomere length and telomerase activity in combination with other prognostic parameters complete the risk profile of B-CLL patients and might serve for an easy decision on optimal treatment strategy. (en)
Title	Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia (en)
skos:prefLabel	Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia (en)
skos:notation	RIV/00023736:_____/10:00008339!RIV11-MZ0-00023736
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LC535), P(NR9244), Z(MSM0021620808), Z(MZ0VFN2005)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Schwarz, Jiří Včelíková, Soňa Michalová, Kyra Šárová, Iveta Březinová, Jana Izáková, Silvia Čechová, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav hematologie a krevní transfúze
http://linked.open...dnocenehoVysledku	292164
http://linked.open...ai/riv/idVysledku	RIV/00023736:_____/10:00008339
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	B-chronic lymphocytic leukemia; telomere length; telomerase activity; chromosomal aberrations; prognosis (en)
http://linked.open.../riv/klicoveSlovo	telomerase activity B-chronic lymphocytic leukemia chromosomal aberrations prognosis telomere length
http://linked.open...odStatuVydavatele	SK - Slovenská republika
http://linked.open...ontrolniKodProRIV	[C5BAD146ED37]
http://linked.open...i/riv/nazevZdroje	Neoplasma
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	17 (xsd:int)
http://linked.open...vavai/riv/projekt	Chromosome dynamics and organization during the cell cycle in normal and pathologic conditions Combined molecular biology and molecular cytogenetic analysis of genomic changes in patients with chronic lymphocytic leukemia
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	57
http://linked.open...iv/tvurceVysledku	Březinová, Jana Karban, J. Michalová, Kyra Trněný, M. Čechová, Hana Schwarz, Jiří Berková, A. Zemanová, Z. Cmunt, E. Zemanová, M. Šárová, Iveta Izáková, Sylvia Včelíková, Soňa Grosová, L. Lizcová, L. Malinová, E. Tajtlová, J.
http://linked.open...ain/vavai/riv/wos	000277412800004
http://linked.open...n/vavai/riv/zamer	Molekulárně biologické, genetické a epigenetické aspekty vzniku a rozvoje modelových tumorů dospělého věku. Význam pro epidemiologii, časnou diagnostiku a léčbu Diagnosis and treatment of inherited disorders II
issn	0028-2685
number of pages	7 (xsd:int)

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