About: Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias

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About: Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The CCAAT/enhancer binding protein alpha (C/EBPalpha) is a member of a family of leucine zipper transcription factors and plays important roles in myeloid differentiation. Learning more about the precise molecular functions of this transcription factor and how these are affected by leukemogenic mutations should lead to an improved understanding of the cellular functions that are disrupted in patients with acute myeloid leukemia (AML) The CCAAT/enhancer binding protein alpha (C/EBPalpha) is a member of a family of leucine zipper transcription factors and plays important roles in myeloid differentiation. Learning more about the precise molecular functions of this transcription factor and how these are affected by leukemogenic mutations should lead to an improved understanding of the cellular functions that are disrupted in patients with acute myeloid leukemia (AML) (en) CCAAT/enhancer binding protein alpha (C/EBPalpha) je členem rodiny transkripčních faktorů obsahujících leucinový zip a hraje důležitou úlohy v diferenciaci myeloidních buněk. Detailnější studium tohoto transkripčního faktoru a jak je ovlivněn mutacemi zahrnutými v leukogeneze by měla usnadnit pochopení jak jsou jeho buněčné funkce porušeny u pacientů s akutní myeloidní leukémií (AML) (cs)
Title	Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias Aktivita transkripčního faktoru C/EBPalpha inhibující růst buněk, jeho úloha v hematopoeze a jeho nádor potlačující a naopak onkogenní vlastnosti u leukémií (cs) Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias (en)
skos:prefLabel	Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias Aktivita transkripčního faktoru C/EBPalpha inhibující růst buněk, jeho úloha v hematopoeze a jeho nádor potlačující a naopak onkogenní vlastnosti u leukémií (cs) Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias (en)
skos:notation	RIV/00023736:_____/07:00007131!RIV08-MZ0-00023736
http://linked.open.../vavai/riv/strany	97;108
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NR9045)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Fuchs, Ota
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav hematologie a krevní transfúze
http://linked.open...dnocenehoVysledku	423706
http://linked.open...ai/riv/idVysledku	RIV/00023736:_____/07:00007131
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cell cycle; proliferation; differentiation; leukemia; C/EBPalpha; tumor suppressor (en)
http://linked.open.../riv/klicoveSlovo	tumor suppressor C/EBPalpha leukemia cell cycle differentiation proliferation
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[633E1FCFA931]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of RUNX1, EVI1 and CEBPA genes in the pathogenesis of leukemias and pre-leukemias
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Fuchs, Ota
issn	0015-5500
number of pages	12 (xsd:int)

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