About: Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells.     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • The effects of Imatinib mesylate on CML cell lines K562 and JURL-MK1 were compared. Imatinib mesylate arrested both cell lines in G0/G1 phase and induced apoptosis that proceeded faster in JURL-MK1 cells and occurred in larger fraction of cell population. In addition, the erythroid differentiation was triggered in both cell lines. Apoptosis and the erythroid differentiation are parallel effects of Imatinib mesylate and their relative contributions and kinetics are related to the differentiation stage of treated cells.
  • The effects of Imatinib mesylate on CML cell lines K562 and JURL-MK1 were compared. Imatinib mesylate arrested both cell lines in G0/G1 phase and induced apoptosis that proceeded faster in JURL-MK1 cells and occurred in larger fraction of cell population. In addition, the erythroid differentiation was triggered in both cell lines. Apoptosis and the erythroid differentiation are parallel effects of Imatinib mesylate and their relative contributions and kinetics are related to the differentiation stage of treated cells. (en)
  • Byly porovnány účinky Imatinib mesylátu na CML buněčné linie K562 a JURL-MK1. U obou linií došlo k zastavení buněčného cyklu v G0/G1 fázi a byla indukována apoptoza jež u buněk JURL-MK1 probíhala rychleji a u větší části buněčné populace. Dále byla u obou linií navozena erytroidní diferenciace. Apoptoza a erytroidní diferenciace jsou paralelními účinky Imatinib mesylátu jejichž relativní příspěvky a kinetiky jsou závislé na diferenciačním stavu buněk. (cs)
Title
  • Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells.
  • Rychlá apoptóza a erytroidní diferenciace vyvolané účinkem imatinib mesylátu na buněčné linie K 562 a JURL-MK1 (cs)
  • Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells. (en)
skos:prefLabel
  • Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells.
  • Rychlá apoptóza a erytroidní diferenciace vyvolané účinkem imatinib mesylátu na buněčné linie K 562 a JURL-MK1 (cs)
  • Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells. (en)
skos:notation
  • RIV/00023736:_____/04:I0000035!RIV/2005/MZ0/L33005/N
http://linked.open.../vavai/riv/strany
  • 36
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NL7681)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 564173
http://linked.open...ai/riv/idVysledku
  • RIV/00023736:_____/04:I0000035
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Imatinib mesylate;STI571;leukemia;apoptosis;erythroid differentiation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [AAE7D1E3A5C0]
http://linked.open...v/mistoKonaniAkce
  • Cascais
http://linked.open...i/riv/mistoVydani
  • Cascais
http://linked.open...i/riv/nazevZdroje
  • 5th interdisciplinary conference mechanisms of cell death and disease : advances in therapeutic intervention and drug development
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Hrkal, Zbyněk
  • Grebeňová, Dana
  • Kuželová, Kateřina
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • ESH and MD Anderson Cancer Center
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 24 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software