About: Effect of TGF--, inhibitors of mitogen-activated protein kinases and proteasome inhibitor on TGF-- receptors mRNAs, Smad mRNAs and target protein Smad mRNAs and target protein p21/CIP1/WAF1 mRNA levels in CTV-1 leukaemia cell line.

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About: Effect of TGF--, inhibitors of mitogen-activated protein kinases and proteasome inhibitor on TGF-- receptors mRNAs, Smad mRNAs and target protein Smad mRNAs and target protein p21/CIP1/WAF1 mRNA levels in CTV-1 leukaemia cell line. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Exogenous TGF- -1 reduced Smad 1-5 mRNA levels and also reduced TGF-- receptors mRNA levels in human leukemia cell line CTV-1 established from a patient with relapsed acute monoblastic leukemia and bought from the DSMZ-German Collection of Microorganisms and Cell Cultures. The heterozygous mutation in Smad4 gene described earlier was not found. Exogenous TGF- -1 reduced Smad 1-5 mRNA levels and also reduced TGF-- receptors mRNA levels in human leukemia cell line CTV-1 established from a patient with relapsed acute monoblastic leukemia and bought from the DSMZ-German Collection of Microorganisms and Cell Cultures. The heterozygous mutation in Smad4 gene described earlier was not found. (en) Přidaný TGF--1 snižuje hladiny Smad 1-5 mRNA a rovněž hladiny receptorů pro TGF-- u lidských leukemických buněk línie CTV-1 ustavených z pacienta s relapsem akutní monoblastické leukémie a získaných z německé banky pro mikroorganismy a buněčné kultury. Dříve popsaná heterozygotní mutace v genu pro Smad4 však nebyla nalezena. (cs)
Title	Effect of TGF--, inhibitors of mitogen-activated protein kinases and proteasome inhibitor on TGF-- receptors mRNAs, Smad mRNAs and target protein Smad mRNAs and target protein p21/CIP1/WAF1 mRNA levels in CTV-1 leukaemia cell line. Effect of TGF--, inhibitors of mitogen-activated protein kinases and proteasome inhibitor on TGF-- receptors mRNAs, Smad mRNAs and target protein Smad mRNAs and target protein p21/CIP1/WAF1 mRNA levels in CTV-1 leukaemia cell line. (en) Vliv TGF--, inhibitorů proteinkinas aktivovaných mitogeny a inhibitorů proteasomů na hladiny mRNA receptorů pro TGF--, Smad mRNA a mRNA pro cílový protein p21/CIP1/WAF1 u linie leukemických buněk CTV-1. (cs)
skos:prefLabel	Effect of TGF--, inhibitors of mitogen-activated protein kinases and proteasome inhibitor on TGF-- receptors mRNAs, Smad mRNAs and target protein Smad mRNAs and target protein p21/CIP1/WAF1 mRNA levels in CTV-1 leukaemia cell line. Effect of TGF--, inhibitors of mitogen-activated protein kinases and proteasome inhibitor on TGF-- receptors mRNAs, Smad mRNAs and target protein Smad mRNAs and target protein p21/CIP1/WAF1 mRNA levels in CTV-1 leukaemia cell line. (en) Vliv TGF--, inhibitorů proteinkinas aktivovaných mitogeny a inhibitorů proteasomů na hladiny mRNA receptorů pro TGF--, Smad mRNA a mRNA pro cílový protein p21/CIP1/WAF1 u linie leukemických buněk CTV-1. (cs)
skos:notation	RIV/00023736:_____/04:I0000029!RIV/2005/MZ0/L33005/N
http://linked.open.../vavai/riv/strany	S66
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NC7605)
http://linked.open...iv/cisloPeriodika	S2
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Fuchs, Ota Benson, Veronika Provazníková, Dana Pešlová, Gabriela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav hematologie a krevní transfúze
http://linked.open...dnocenehoVysledku	562054
http://linked.open...ai/riv/idVysledku	RIV/00023736:_____/04:I0000029
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	TGF--;Smad mRNA;TGF-- receptors mRNA;p21/CIP1/WAF1;proteasome inhibitors;MAPK inhibitors;CTV-1 cells (en)
http://linked.open.../riv/klicoveSlovo	Smad mRNA CTV-1 cells MAPK inhibitors TGF-- TGF-- receptors mRNA p21/CIP1/WAF1 proteasome inhibitors
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[3FDA91148FBF]
http://linked.open...i/riv/nazevZdroje	Hematology Journal
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of transforming growth factor beta (TGFb) signalig pathway in hematological malignancies and in myelodysplastic syndrome
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	5
http://linked.open...iv/tvurceVysledku	Fuchs, Ota Provazníková, Dana Pešlová, Gabriela Ullmannová, Veronika
issn	1466-4860
number of pages	1 (xsd:int)

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