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  • Zastavení proliferace buněk HL60 fotodynamickou terapií indukovalo apoptotický proces, avšak nukleolární velikost a densita se u apoptotických buněk ve srovnání s kontrolami nezměnila. Velké a densitní nukleoly u apoptotických buněk nejsou spojeny s biosyntetickou či proliferační aktiviotou. (cs)
  • The present study was undertaken to provide more information on the nucleolar size and density in mononucleolar blastic granulocytic precursors represented by HL-60 cells the proliferation of which was blocked by photodynamic treatment (PDT) which induced apoptotic process without preceding terminal maturation. Arrest of cell proliferation of HL60 cells by photodynamic treatment induced an apoptotic process that was not paralleled by changes in the nucleolar size and density. Large and dense nucleoli in apoptotic cells are not related to the nucleolar biosynthetic or cell proliferation activity.
  • The present study was undertaken to provide more information on the nucleolar size and density in mononucleolar blastic granulocytic precursors represented by HL-60 cells the proliferation of which was blocked by photodynamic treatment (PDT) which induced apoptotic process without preceding terminal maturation. Arrest of cell proliferation of HL60 cells by photodynamic treatment induced an apoptotic process that was not paralleled by changes in the nucleolar size and density. Large and dense nucleoli in apoptotic cells are not related to the nucleolar biosynthetic or cell proliferation activity. (en)
Title
  • A short note on the nucleolar size and density in apoptotic leukemic granulocytic precursors (HL-60 cells).
  • Nukleolární velikost a densita u apoptotických leukemických buněk HL-60. (cs)
  • A short note on the nucleolar size and density in apoptotic leukemic granulocytic precursors (HL-60 cells). (en)
skos:prefLabel
  • A short note on the nucleolar size and density in apoptotic leukemic granulocytic precursors (HL-60 cells).
  • Nukleolární velikost a densita u apoptotických leukemických buněk HL-60. (cs)
  • A short note on the nucleolar size and density in apoptotic leukemic granulocytic precursors (HL-60 cells). (en)
skos:notation
  • RIV/00023736:_____/04:I0000004!RIV/2005/MZ0/L33005/N
http://linked.open.../vavai/riv/strany
  • 791-796
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA523/04/0755), P(NC7603), P(NL7681), Z(MZ00237360001)
http://linked.open...iv/cisloPeriodika
  • 7
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 553175
http://linked.open...ai/riv/idVysledku
  • RIV/00023736:_____/04:I0000004
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • nucleolar size;nucleolar density;apoptosis;HL-60 cells (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [9B412A3ED394]
http://linked.open...i/riv/nazevZdroje
  • Life Sciences
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 75
http://linked.open...iv/tvurceVysledku
  • Hrkal, Zbyněk
  • Marinov, Iuri
  • Smetana, Karel
  • Souček, Josef
  • Busch, H.
  • Chan, P. K.
http://linked.open...n/vavai/riv/zamer
issn
  • 0024-3205
number of pages
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