About: Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins.

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About: Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Zinc is an essential trace element required by all living organisms. It plays critical roles in a wide variety of biochemical processes including growth, development and reproduction. In biological systems very little amount of zinc is free in solution. Zinc carries out his biological role as divalent cation bound to proteins. Zinc is a cofactor required for function of over 300 mammalian enzymes from all 6 major functional enzyme classes. In addition over thousand of genes in the human genome encode proteins with zinc finger domains. These proteins function as transcriptional regulators in many cellular events and play also role in protein-protein interactions. In humans, the significance of zinc is illustrated by devastating effect of zinc deficiency inducing dermatitis, diminished immune response, decreased healing and neurological changes. Zinc is an essential trace element required by all living organisms. It plays critical roles in a wide variety of biochemical processes including growth, development and reproduction. In biological systems very little amount of zinc is free in solution. Zinc carries out his biological role as divalent cation bound to proteins. Zinc is a cofactor required for function of over 300 mammalian enzymes from all 6 major functional enzyme classes. In addition over thousand of genes in the human genome encode proteins with zinc finger domains. These proteins function as transcriptional regulators in many cellular events and play also role in protein-protein interactions. In humans, the significance of zinc is illustrated by devastating effect of zinc deficiency inducing dermatitis, diminished immune response, decreased healing and neurological changes. (en)
Title	Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins. Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins. (en)
skos:prefLabel	Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins. Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins. (en)
skos:notation	RIV/00023736:_____/03:00000051!RIV/2004/GA0/L33004/N
http://linked.open.../vavai/riv/strany	157;170
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA204/00/1059), P(NB6574)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Babušiak, Marek Vyoral, Daniel Petrák, Jiří Fuchs, Ota
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav hematologie a krevní transfúze
http://linked.open...dnocenehoVysledku	625938
http://linked.open...ai/riv/idVysledku	RIV/00023736:_____/03:00000051
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	zinc; metallothionein; transport proteins ZIP and ZnT; zinc finger proteins; gene expression (en)
http://linked.open.../riv/klicoveSlovo	gene expression zinc zinc finger proteins metallothionein transport proteins ZIP and ZnT
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[A507362A58BA]
http://linked.open...i/riv/nazevZdroje	Sborník lékařský
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	The identification of zinc transporters in intestinal epithelial cells, erythropoietic cells and serum Mechanisms of iron absorption and characterization of proteins involved. Funkction of the protein HFE coded by the gene mutated in hereditary hemochomatosis
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	Z104
http://linked.open...iv/tvurceVysledku	Petrák, Jiří Vyoral, Daniel Fuchs, Ota Babušiak, Marek
issn	0036-5327
number of pages	14 (xsd:int)

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