About: Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells.

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About: Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We studied the mechanism of the cytotoxic effect of 5- aminolevulinic acid-based photodynamic therapy (ALA-PDT) on the human promyelocytic leukemia cell line HL60 using biochemical and electron microscopy methods. ALA-PDT activates the mitochondrial apoptotic pathway, disrupts calcium homeostasis and induces stress in the endoplasmic reticulum. We studied the mechanism of the cytotoxic effect of 5- aminolevulinic acid-based photodynamic therapy (ALA-PDT) on the human promyelocytic leukemia cell line HL60 using biochemical and electron microscopy methods. ALA-PDT activates the mitochondrial apoptotic pathway, disrupts calcium homeostasis and induces stress in the endoplasmic reticulum. (en)
Title	Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells. Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells. (en)
skos:prefLabel	Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells. Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells. (en)
skos:notation	RIV/00023736:_____/03:00000043!RIV/2004/GA0/L33004/N
http://linked.open.../vavai/riv/strany	71;85
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA303/01/1445), P(NC5883), Z(MZ00237360001)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Grebeňová, Dana Kuželová, Kateřina Souček, Josef Pluskalová, Michaela Smetana, Karel Fuchs, Ota Hrkal, Zbyněk Marinov, Iuri
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav hematologie a krevní transfúze
http://linked.open...dnocenehoVysledku	615659
http://linked.open...ai/riv/idVysledku	RIV/00023736:_____/03:00000043
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	photodynamic therapy; 5-aminolevulinic acid; HL-60 cell line; apoptosis; mitochondrion; endoplasmic reticulum (en)
http://linked.open.../riv/klicoveSlovo	endoplasmic reticulum mitochondrion photodynamic therapy apoptosis HL-60 cell line 5-aminolevulinic acid
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[306608C3A9E2]
http://linked.open...i/riv/nazevZdroje	Journal of Photochemistry and Photobiology B
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Analysis of the proteome of malignant cells two-dimensional elektrophoresis and mass spectrometry Molecular mechanism of cancer therapy based on photoactivation of induced endogenous protoporphyrin IX (ALA-PDT).
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	69
http://linked.open...iv/tvurceVysledku	Hrkal, Zbyněk Marinov, Iuri Smetana, Karel Grebeňová, Dana Kuželová, Kateřina Fuchs, Ota Souček, Josef Pluskalová, Michaela Jarolím, P. Cajthamlová, H.
http://linked.open...n/vavai/riv/zamer	Pathophysiology,diagnosis, and treatment of blood malignancies and blood coagulation disorders
issn	1011-1344
number of pages	15 (xsd:int)

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