About: Immunotherapy with dendritic cells infected with recombinant vaccinia viruses expressing HPV16 E7LAMP gene.     Goto   Sponge   NotDistinct   Permalink

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Description
  • Imunization with DC transduced with recombinant vaccinia viruses (rVV) expressing E7 protein of HPV16 induced better protection against growth of TC-1 tumors than immunization with the same dose of rVV. The increase of immunogenicity was highly significant with attenuated virus MVA. Production of large amount of IL12 by rVV entirely abolished immunogenicity of transduced DCs.
  • Imunization with DC transduced with recombinant vaccinia viruses (rVV) expressing E7 protein of HPV16 induced better protection against growth of TC-1 tumors than immunization with the same dose of rVV. The increase of immunogenicity was highly significant with attenuated virus MVA. Production of large amount of IL12 by rVV entirely abolished immunogenicity of transduced DCs. (en)
Title
  • Immunotherapy with dendritic cells infected with recombinant vaccinia viruses expressing HPV16 E7LAMP gene.
  • Immunotherapy with dendritic cells infected with recombinant vaccinia viruses expressing HPV16 E7LAMP gene. (en)
skos:prefLabel
  • Immunotherapy with dendritic cells infected with recombinant vaccinia viruses expressing HPV16 E7LAMP gene.
  • Immunotherapy with dendritic cells infected with recombinant vaccinia viruses expressing HPV16 E7LAMP gene. (en)
skos:notation
  • RIV/00023736:_____/03:00000013!RIV/2004/GA0/L33004/N
http://linked.open.../vavai/riv/strany
  • 65;65
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA301/01/0985)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 609843
http://linked.open...ai/riv/idVysledku
  • RIV/00023736:_____/03:00000013
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • vaccinia virus; vaccine; papillomavirus; E7 (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [E6B859F63DA3]
http://linked.open...v/mistoKonaniAkce
  • Cambridge
http://linked.open...i/riv/mistoVydani
  • Cambridge
http://linked.open...i/riv/nazevZdroje
  • HPV vaccines and immunotherapies : symposium handbook
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Hainz, Petr
  • Kutinová, Luďa
  • Němečková, Šárka
  • Šubrtová, Jana
  • Gabriel, Pavel
  • Otáhal, P.
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • Robinson College University of Cambridge
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