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  • A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: is extracorporeal membrane oxygenation (ECMO) superior to dedicated ventricular assist device (VAD) in patients with acutely failing allograft following transplantation. Altogether, 162 papers were found using the reported search, of which 8 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. Two studies provide data only for ECMO-treated patients, in three, the authors describe their experiences with Levitronix CentriMag and three studies directly compare the outcomes of ECMO and VAD support. The survival ranges from 40 to 74% in patients rescued with ECMO compared with 33-60% in patients supported with dedicated VAD. We conclude that there is insufficient evidence to prefer ECMO over VAD and the optimal modality of mechanical circulatory support (MCS) following heart transplantation should be determined by the surgeon and institutional experience and dependent on the extent and severity of myocardial dysfunction and the presence or absence of associated respiratory insufficiency.
  • A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: is extracorporeal membrane oxygenation (ECMO) superior to dedicated ventricular assist device (VAD) in patients with acutely failing allograft following transplantation. Altogether, 162 papers were found using the reported search, of which 8 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. Two studies provide data only for ECMO-treated patients, in three, the authors describe their experiences with Levitronix CentriMag and three studies directly compare the outcomes of ECMO and VAD support. The survival ranges from 40 to 74% in patients rescued with ECMO compared with 33-60% in patients supported with dedicated VAD. We conclude that there is insufficient evidence to prefer ECMO over VAD and the optimal modality of mechanical circulatory support (MCS) following heart transplantation should be determined by the surgeon and institutional experience and dependent on the extent and severity of myocardial dysfunction and the presence or absence of associated respiratory insufficiency. (en)
Title
  • What is the optimal mode of mechanical support in transplanted patients with acute graft failure?
  • What is the optimal mode of mechanical support in transplanted patients with acute graft failure? (en)
skos:prefLabel
  • What is the optimal mode of mechanical support in transplanted patients with acute graft failure?
  • What is the optimal mode of mechanical support in transplanted patients with acute graft failure? (en)
skos:notation
  • RIV/00023001:_____/13:00058544!RIV14-MZ0-00023001
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • N
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 117293
http://linked.open...ai/riv/idVysledku
  • RIV/00023001:_____/13:00058544
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Extracorporeal membrane oxygenation; Circulatory assist devices; heart; Review Transplantation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [0A1413FEE269]
http://linked.open...i/riv/nazevZdroje
  • Interactive cardiovascular and thoracic surgery
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 16
http://linked.open...iv/tvurceVysledku
  • Netuka, Ivan
  • Pirk, Jan
  • Szárszoi, Ondrej
  • Urban, Marian
http://linked.open...ain/vavai/riv/wos
  • 000316298300029
issn
  • 1569-9293
number of pages
http://bibframe.org/vocab/doi
  • 10.1093/icvts/ivs546
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