About: Prediction of organ transplant rejection by HLA-specific and non-HLA antibodies brief literature review

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About: Prediction of organ transplant rejection by HLA-specific and non-HLA antibodies brief literature review Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://onlinelibrary.wiley.com/doi/10.1111/j.1744-313X.2012.01139.x/abstract
Description	The application of soli-phase assays for detection and definition of Human luecocyty antigen (HLA)- specific antibodies has significantly facilitated the diagnosis and monitoring of treatment of antibody-mediated tejection (AMR). There is, however, a major discusion in the literature concerning the clinical relevance of the use of the Luminex technique for the prediction of celluar and/or AMR and survival. This may be explained on one hand by the complexities of the method and on the other by variations in patient demographic charakteristics, immunosuppression and other factors. As far as non-HLA antibodies, it is clear that they may induce AMR; nevertheless,a difficult problem in their definition remains the fact that most of the non-HLA antigens still remain to be identified. Hereby is a short literature review of several recent publications discussing the role of HLA- and non-HLA-specific antibodies in organ transplant rejection and survival. The application of soli-phase assays for detection and definition of Human luecocyty antigen (HLA)- specific antibodies has significantly facilitated the diagnosis and monitoring of treatment of antibody-mediated tejection (AMR). There is, however, a major discusion in the literature concerning the clinical relevance of the use of the Luminex technique for the prediction of celluar and/or AMR and survival. This may be explained on one hand by the complexities of the method and on the other by variations in patient demographic charakteristics, immunosuppression and other factors. As far as non-HLA antibodies, it is clear that they may induce AMR; nevertheless,a difficult problem in their definition remains the fact that most of the non-HLA antigens still remain to be identified. Hereby is a short literature review of several recent publications discussing the role of HLA- and non-HLA-specific antibodies in organ transplant rejection and survival. (en)
Title	Prediction of organ transplant rejection by HLA-specific and non-HLA antibodies brief literature review Prediction of organ transplant rejection by HLA-specific and non-HLA antibodies brief literature review (en)
skos:prefLabel	Prediction of organ transplant rejection by HLA-specific and non-HLA antibodies brief literature review Prediction of organ transplant rejection by HLA-specific and non-HLA antibodies brief literature review (en)
skos:notation	RIV/00023001:_____/13:00057908!RIV14-MZ0-00023001
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(NT11262)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Slavčev, Antonij
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	98595
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/13:00057908
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	review; literature; brief; antibodies; non-HLA; and; HLA-specific; rejection; transplant; organ; Prediction (en)
http://linked.open.../riv/klicoveSlovo	transplant Prediction antibodies literature review and brief organ rejection HLA-specific non-HLA
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[1609006856C4]
http://linked.open...i/riv/nazevZdroje	International journal of immunogenetics
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	Approach to patients with preformed antibodies before heart transplantation.
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	40
http://linked.open...iv/tvurceVysledku	Slavčev, Antonij
http://linked.open...ain/vavai/riv/wos	000315966400001
issn	1744-3121
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/j.1744-313X.2012.01139.x

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