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Description
  • It is demonstrated that glycogen as a biodegradable and inexpensive material coming from renewable resources can be used as a carrier for the construction of in vivo imaging nanoagents. The model system considered is composed of glycogen modified with gadolinium and fluorescent labels. Systematic studies of properties of these nanocarriers by a variety of physical methods and results of in vivo tests of biodegradability are reported. This represents, to the authors' best knowledge, the first such use of glycogen.
  • It is demonstrated that glycogen as a biodegradable and inexpensive material coming from renewable resources can be used as a carrier for the construction of in vivo imaging nanoagents. The model system considered is composed of glycogen modified with gadolinium and fluorescent labels. Systematic studies of properties of these nanocarriers by a variety of physical methods and results of in vivo tests of biodegradability are reported. This represents, to the authors' best knowledge, the first such use of glycogen. (en)
Title
  • Glycogen as a biodegradable construction nanomaterial for in vivo use
  • Glycogen as a biodegradable construction nanomaterial for in vivo use (en)
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  • Glycogen as a biodegradable construction nanomaterial for in vivo use
  • Glycogen as a biodegradable construction nanomaterial for in vivo use (en)
skos:notation
  • RIV/00023001:_____/12:00056113!RIV13-MZ0-00023001
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(GA202/09/2078), P(GAP108/12/0640), P(GAP208/10/1600), P(GPP207/10/P054), Z(AV0Z40500505)
http://linked.open...iv/cisloPeriodika
  • 12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
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http://linked.open...dnocenehoVysledku
  • 138244
http://linked.open...ai/riv/idVysledku
  • RIV/00023001:_____/12:00056113
http://linked.open...riv/jazykVysledku
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  • nanoparticles; in vivo imaging; glycogen; biodegradable (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [3596398DD2B5]
http://linked.open...i/riv/nazevZdroje
  • Macromolecular bioscience
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 12
http://linked.open...iv/tvurceVysledku
  • Kovář, Jan
  • Štěpánek, Petr
  • Jirák, Daniel
  • Bogomolova, Anna
  • Bals, Sara
  • Filippov, Sergey K.
  • Hruby, Martin
  • Kucka, Jan
  • Sedláček, Ondrej
  • Turner, Stuart
  • Vetrik, Miroslav
http://linked.open...ain/vavai/riv/wos
  • 000312242600016
http://linked.open...n/vavai/riv/zamer
issn
  • 1616-5187
number of pages
http://bibframe.org/vocab/doi
  • 10.1002/mabi.201200294
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