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  • Aims: Electrical storm (ES) adversely affects prognosis of patients and may become a life-threatening event. Catheter ablation (CA) has been proposed for the treatment of ES. Our goal was to evaluate the efficacy of CA ablation both in acute and long-term suppression of ES. Methods and results: Fifty consecutive patients with coronary artery disease (38), idiopathic dilated cardiomyopathy (5), arrhythmogenic right ventricular cardiomyopathy (6), and/or with combined aetiology (1) underwent CA for ES. Mean left ventricular ejection fraction (LVEF) was 29 +/- 11%. All patients underwent electroanatomical mapping, and CA was performed to abolish all inducible ventricular arrhythmias. The ES was suppressed by CA in 84% of patients. During the follow-up of 18 +/- 16 months, 24 patients had no recurrences of any ventricular tachycardia (VT; 48%). Repeated procedure was necessary to suppress the recurrent ES in 13 cases (26%). Statistical analysis revealed that low LVEF (22 +/- 3 vs. 31 +/- 12%; P < 0.001), increased LVend-diastolic diameter (72 +/- 9.1vs. 64 +/- 8.9 mm; P = 0.0135), and renal insufficiency (P < 0.001) were the univariate predictors of early mortality or necessity for heart transplantation. Recurrence of ES despite previous CA procedure was associated with a higher risk of death or heart transplant during follow-up (P < 0.05). Conclusion: Catheter ablation is effective in acute suppression of ES and often represents a life-saving therapy. In the long term, it prevents recurrences of any VT in about half of the treated patients.
  • Aims: Electrical storm (ES) adversely affects prognosis of patients and may become a life-threatening event. Catheter ablation (CA) has been proposed for the treatment of ES. Our goal was to evaluate the efficacy of CA ablation both in acute and long-term suppression of ES. Methods and results: Fifty consecutive patients with coronary artery disease (38), idiopathic dilated cardiomyopathy (5), arrhythmogenic right ventricular cardiomyopathy (6), and/or with combined aetiology (1) underwent CA for ES. Mean left ventricular ejection fraction (LVEF) was 29 +/- 11%. All patients underwent electroanatomical mapping, and CA was performed to abolish all inducible ventricular arrhythmias. The ES was suppressed by CA in 84% of patients. During the follow-up of 18 +/- 16 months, 24 patients had no recurrences of any ventricular tachycardia (VT; 48%). Repeated procedure was necessary to suppress the recurrent ES in 13 cases (26%). Statistical analysis revealed that low LVEF (22 +/- 3 vs. 31 +/- 12%; P < 0.001), increased LVend-diastolic diameter (72 +/- 9.1vs. 64 +/- 8.9 mm; P = 0.0135), and renal insufficiency (P < 0.001) were the univariate predictors of early mortality or necessity for heart transplantation. Recurrence of ES despite previous CA procedure was associated with a higher risk of death or heart transplant during follow-up (P < 0.05). Conclusion: Catheter ablation is effective in acute suppression of ES and often represents a life-saving therapy. In the long term, it prevents recurrences of any VT in about half of the treated patients. (en)
Title
  • Catheter ablation of electrical storm in patients with structural heart disease
  • Catheter ablation of electrical storm in patients with structural heart disease (en)
skos:prefLabel
  • Catheter ablation of electrical storm in patients with structural heart disease
  • Catheter ablation of electrical storm in patients with structural heart disease (en)
skos:notation
  • RIV/00023001:_____/11:00002738!RIV12-MSM-00023001
http://linked.open...avai/riv/aktivita
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  • P(1M0510)
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  • 1
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  • 189302
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  • RIV/00023001:_____/11:00002738
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  • Electrical storm; Catheter ablation; Ventricular tachycardia; Implantable cardioverter-defibrillator (en)
http://linked.open.../riv/klicoveSlovo
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [F915EA716027]
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  • Europace
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  • 13
http://linked.open...iv/tvurceVysledku
  • Bytešník, Jan
  • Kautzner, Josef
  • Koželuhová, Markéta
  • Peichl, Petr
  • Vančura, Vlastimil
  • Wichterle, Dan
  • Čihák, Robert
http://linked.open...ain/vavai/riv/wos
  • 000285417000022
issn
  • 1099-5129
number of pages
http://bibframe.org/vocab/doi
  • 10.1093/europace/euq364
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