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rdf:type
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Description
| - It is well known that the consumption of moderate doses of alcohol leads to the increase of HDL-cholesterol (HDL-C). Atheroprotectivity of HDL particles is based primarily on their role in reverse cholesterol transport (RCT). In the study with a crossover design 13 male volunteers were studied in two different regimens: i) drinking of 36 g alcohol daily and ii) drinking only non-alcoholic beverages, to test whether alcohol-induced increase of HDL cholesterol can affect cholesterol efflux (CHE) from cell culture of labeled human macrophages. Alcohol consumption induced significant (p<0.05) increases of HDL cholesterol from 1.25?0.32 to 1.34?0.38 mmol/l and Apo A1 from 1.34?0.16 to 1.44?0.19 g/l. These changes were combined with a slight increase of cholesterol efflux from 13.8?2.15 to 14.9?1.85 % (p=0.059). There were significant correlations between individual changes of HDL-C and Apo A1 concentrations and individual changes of CHE (0.51 and 0.60, respectively). In conclusion, moderate alcohol co
- It is well known that the consumption of moderate doses of alcohol leads to the increase of HDL-cholesterol (HDL-C). Atheroprotectivity of HDL particles is based primarily on their role in reverse cholesterol transport (RCT). In the study with a crossover design 13 male volunteers were studied in two different regimens: i) drinking of 36 g alcohol daily and ii) drinking only non-alcoholic beverages, to test whether alcohol-induced increase of HDL cholesterol can affect cholesterol efflux (CHE) from cell culture of labeled human macrophages. Alcohol consumption induced significant (p<0.05) increases of HDL cholesterol from 1.25?0.32 to 1.34?0.38 mmol/l and Apo A1 from 1.34?0.16 to 1.44?0.19 g/l. These changes were combined with a slight increase of cholesterol efflux from 13.8?2.15 to 14.9?1.85 % (p=0.059). There were significant correlations between individual changes of HDL-C and Apo A1 concentrations and individual changes of CHE (0.51 and 0.60, respectively). In conclusion, moderate alcohol co (en)
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Title
| - May alcohol-induced increase of HDL be considered as atheroprotective?
- May alcohol-induced increase of HDL be considered as atheroprotective? (en)
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skos:prefLabel
| - May alcohol-induced increase of HDL be considered as atheroprotective?
- May alcohol-induced increase of HDL be considered as atheroprotective? (en)
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skos:notation
| - RIV/00023001:_____/10:00002265!RIV11-MZ0-00023001
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00023001:_____/10:00002265
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - reverse cholesterol transport; cholesterol efflux; lipoproteins; alcohol consumption (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Králová Lesná, Ivana
- Poledne, Rudolf
- Suchánek, Pavel
- Stávek, Petr
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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