About: Coronary calcium score in renal transplant recipients

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000210082
Description	Background: Coronary calcium score (CCS) is established as an index for the risk of coronary heart disease (CHD). The aim of this prospective study was to assess changes in CCS in patients 1 year after kidney transplantation (KTx). Method: A total of 221 consecutive renal transplant recipients were enrolled in our prospective study (140 males/81 females). CCS was analyzed by spiral multidetector CT at baseline and 1 year after KTx. Bone mineral density (BMD) was measured in the lumbar spine (L-BMD) and femur (F-BMD). Results: The mean CCS was 539 +/- 1,033 at baseline. 33% of the patients had a CCS of 0, and 33% of patients had a CCS of >401. A negative correlation was found between F-BMD and CCS, but no correlation was found between L-BMD and CCS. Using CCS, a positive correlation was found between total cholesterol and the age of patients, but no correlation of CCS was found with other biochemical markers of bone and lipid metabolism. One year after transplantation, the mean CCS was 703 +/- 1,253; in 75% of patients the CCS was the same and 25% had a higher CCS. Conclusion: A high risk of CHD was found in 33% of renal graft recipients. No improvement in CCS was found 1 year after KTx. Background: Coronary calcium score (CCS) is established as an index for the risk of coronary heart disease (CHD). The aim of this prospective study was to assess changes in CCS in patients 1 year after kidney transplantation (KTx). Method: A total of 221 consecutive renal transplant recipients were enrolled in our prospective study (140 males/81 females). CCS was analyzed by spiral multidetector CT at baseline and 1 year after KTx. Bone mineral density (BMD) was measured in the lumbar spine (L-BMD) and femur (F-BMD). Results: The mean CCS was 539 +/- 1,033 at baseline. 33% of the patients had a CCS of 0, and 33% of patients had a CCS of >401. A negative correlation was found between F-BMD and CCS, but no correlation was found between L-BMD and CCS. Using CCS, a positive correlation was found between total cholesterol and the age of patients, but no correlation of CCS was found with other biochemical markers of bone and lipid metabolism. One year after transplantation, the mean CCS was 703 +/- 1,253; in 75% of patients the CCS was the same and 25% had a higher CCS. Conclusion: A high risk of CHD was found in 33% of renal graft recipients. No improvement in CCS was found 1 year after KTx. (en)
Title	Coronary calcium score in renal transplant recipients Coronary calcium score in renal transplant recipients (en)
skos:prefLabel	Coronary calcium score in renal transplant recipients Coronary calcium score in renal transplant recipients (en)
skos:notation	RIV/00023001:_____/09:00002756!RIV12-MZ0-00023001
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NR8286)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Adamec, Miloš Bubeníček, Petr Lánská, Věra Teplan, Vladimír Sotorník, Ivo Kautznerová, Dana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	308373
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/09:00002756
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Vascular calcification; Bone disease; Renal transplantation; Metabolic markers, bone; Bone mineral density; Coronary artery disease (en)
http://linked.open.../riv/klicoveSlovo	Renal transplantation Bone disease Metabolic markers Vascular calcification bone Coronary artery disease Bone mineral density
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[3B4B3412C280]
http://linked.open...i/riv/nazevZdroje	Nephron clinical practice
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	DETECTION OF LOW-TURNOVER OSTEOPATHY BEFORE AND AFTER RENAL TRANSPLANTATION
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	112
http://linked.open...iv/tvurceVysledku	Adamec, Miloš Bubeníček, Petr Lánská, Věra Teplan, Vladimír Sotorník, Ivo Kautznerová, Dana
http://linked.open...ain/vavai/riv/wos	000265627400001
issn	1660-2110
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1159/000210082

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