About: Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats

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About: Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The present study was performed to characterize the autoregulatory efficiency of renal blood flow (RBF) and glomerular filtration rate (GFR) and the pressure-natriuresis relationship in transgenic rats with inducible angiotensin II (ANG II)-dependent malignant hypertension (Cyp1a1-Ren-2 rats). Our findings indicate that an the impairment of the pressure-natriuresis mechanism precedes the development of ANG II-dependent malignant in Cyp1a1-Ren-2 transgenic rats. The present study was performed to characterize the autoregulatory efficiency of renal blood flow (RBF) and glomerular filtration rate (GFR) and the pressure-natriuresis relationship in transgenic rats with inducible angiotensin II (ANG II)-dependent malignant hypertension (Cyp1a1-Ren-2 rats). Our findings indicate that an the impairment of the pressure-natriuresis mechanism precedes the development of ANG II-dependent malignant in Cyp1a1-Ren-2 transgenic rats. (en)
Title	Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats (en)
skos:prefLabel	Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats (en)
skos:notation	RIV/00023001:_____/09:00001946!RIV10-MZ0-00023001
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0510), P(GA305/07/0167), P(IAA511700701), Z(MZ000023001), Z(MZ0IKEM2005)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Bürgelová, Marcela Vaňourková, Zdeňka Husková, Zuzana Červenka, Luděk Vaněčková, Ivana Thumová, Monika
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	318664
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/09:00001946
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	angiotensin II levels; autoregulation; glomerular filtration rate; hypertension; inducible transgenic renin gene rats; renal blood flow; renin-angiotensin system; sodium excretion (en)
http://linked.open.../riv/klicoveSlovo	glomerular filtration rate renin-angiotensin system autoregulation renal blood flow hypertension - ischaemic heart disease - cardiac failure - vitamin D angiotensin II levels inducible transgenic renin gene rats sodium excretion
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[A5C0BCF83C33]
http://linked.open...i/riv/nazevZdroje	Journal of Hypertension
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of angiotensin II type 2 receptors in the pathophysiology of renovascular hypertension Centre for cardiovascular research The role of angiotensin-(1-7), a new component of the renin-angiotensin system, in the pathophysiology of two-kidney one-clip Goldblatt hypertension
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	27
http://linked.open...iv/tvurceVysledku	Bürgelová, Marcela Husková, Zuzana Vaněčková, Ivana Vaňourková, Zdeňka Červenka, Luděk Thumová, Monika Mullins, J. Erbanová, M. Kramer, H. Rakušan, D.
http://linked.open...ain/vavai/riv/wos	000265149200019
http://linked.open...n/vavai/riv/zamer	Výzkum kardiovaskulárních nemocí, diabetu a transplantace životně důležitých orgánů Nové aspekty patofyziologie, prevence, diagnostiky a léčby nejzávažnějších onemocnění v české populaci
issn	0263-6352
number of pages	12 (xsd:int)

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