About: Fatty acid binding proteins in adipose tissue: a promising link between metabolic syndrome and atherosclerosis?

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About: Fatty acid binding proteins in adipose tissue: a promising link between metabolic syndrome and atherosclerosis? Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Adipocyte/macrophage fatty acid binding protein has been shown to be closely associated with metabolic syndrome, obesity and development of atherosclerosis. Moreover, A-FABP has been recently suggested as a potential therapeutic target of these abnormalities in animal models. The present review aims to summarize current knowledge on A-FABP functions and regulations both in animal models and humans, since the role of A-FABP in human physiology and disease has not been presently clarified. Adipocyte/macrophage fatty acid binding protein has been shown to be closely associated with metabolic syndrome, obesity and development of atherosclerosis. Moreover, A-FABP has been recently suggested as a potential therapeutic target of these abnormalities in animal models. The present review aims to summarize current knowledge on A-FABP functions and regulations both in animal models and humans, since the role of A-FABP in human physiology and disease has not been presently clarified. (en) Vazebné bílkoviny pro mastné kyseliny v adipocytech a makrofázích jsou asociované s metabolickým syndromem, obezitou a rozvojem aterosklerozy. Zvířecí modely ukazují, že léčebné intervence zaměřené na FABP jsou nadějné. Sdělení shrnuje současné znalosti o FABP, jeho funkcích, regulacích, v experimentálních modelech i u člověka. (cs)
Title	Fatty acid binding proteins in adipose tissue: a promising link between metabolic syndrome and atherosclerosis? Fatty acid binding proteins in adipose tissue: a promising link between metabolic syndrome and atherosclerosis? (en) Vazebné bílkoviny FABP pro mastné kyseliny v tukové tkáni, nadějné pojítko mezi metabolickým syndromem a aterosklerozou? (cs)
skos:prefLabel	Fatty acid binding proteins in adipose tissue: a promising link between metabolic syndrome and atherosclerosis? Fatty acid binding proteins in adipose tissue: a promising link between metabolic syndrome and atherosclerosis? (en) Vazebné bílkoviny FABP pro mastné kyseliny v tukové tkáni, nadějné pojítko mezi metabolickým syndromem a aterosklerozou? (cs)
skos:notation	RIV/00023001:_____/08:00001889!RIV09-MZ0-00023001
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NR8991)
http://linked.open...iv/cisloPeriodika	suppl. 2
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Pelikánová, Terezie Krušinová, Eva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	367735
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/08:00001889
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	metabolic syndrome; atherosclerosis; FABP; adipose tissue (en)
http://linked.open.../riv/klicoveSlovo	FABP adipose tissue atherosclerosis metabolic syndrome
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[FF5D6D0E2006]
http://linked.open...i/riv/nazevZdroje	Diabetes research and clinical practice
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of CNS in the pathophysiology of insulin resistance
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	82
http://linked.open...iv/tvurceVysledku	Pelikánová, Terezie Krušinová, Eva
http://linked.open...ain/vavai/riv/wos	000262141300009
issn	0168-8227
number of pages	8 (xsd:int)

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