About: Soluble CD30 in patients with antibody-mediated rejection of the kidney allograft

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of our retrospective study was to evaluate the clitiical significance of measurement ofthe soluble CD30 (sCD30) molecule for the prediction of antibody-mediated (humoral) rejection (MR). Sixty-two kidney transplant recipients (thirty-one C4d-positive and thirty-one C4dnegative patients) were included inio the study. Soluble CD3n levels were evaluated before transplantation and during periods of graft ftinction deterioration. The median concentrations of the sCD30 molecule were identical in C4d-positive and C4d-negative patients before and atler transplantation (65.5 vs. 65.0 and 28.2 vs. 36.0 U/ml, respectively). C4d+ patients who developed DSA de novo had a tendency to have higher sCD30 levels before transplantation (8O.7+/-53.6 U/ml, n-8) compared wilh C4d-negative patients (65.0+/-33.4 U/ml, / i - 15). Soluble CD3O levels were evaluated as positive and negative (>IOO U/ml and <IOO U/ml respectively) and the sensitivity, specificity and accuracy of sCD30 estimation with regard t The aim of our retrospective study was to evaluate the clitiical significance of measurement ofthe soluble CD30 (sCD30) molecule for the prediction of antibody-mediated (humoral) rejection (MR). Sixty-two kidney transplant recipients (thirty-one C4d-positive and thirty-one C4dnegative patients) were included inio the study. Soluble CD3n levels were evaluated before transplantation and during periods of graft ftinction deterioration. The median concentrations of the sCD30 molecule were identical in C4d-positive and C4d-negative patients before and atler transplantation (65.5 vs. 65.0 and 28.2 vs. 36.0 U/ml, respectively). C4d+ patients who developed DSA de novo had a tendency to have higher sCD30 levels before transplantation (8O.7+/-53.6 U/ml, n-8) compared wilh C4d-negative patients (65.0+/-33.4 U/ml, / i - 15). Soluble CD3O levels were evaluated as positive and negative (>IOO U/ml and <IOO U/ml respectively) and the sensitivity, specificity and accuracy of sCD30 estimation with regard t (en) solubilní CD30; rejekce ledvinného aloštěpu; protilátky; retrospektivní studie (cs)
Title	Soluble CD30 in patients with antibody-mediated rejection of the kidney allograft Solubilní CD30 u pacientů s rejekcí ledvinného aloštěpu zprostředkované protilátkami (cs) Soluble CD30 in patients with antibody-mediated rejection of the kidney allograft (en)
skos:prefLabel	Soluble CD30 in patients with antibody-mediated rejection of the kidney allograft Solubilní CD30 u pacientů s rejekcí ledvinného aloštěpu zprostředkované protilátkami (cs) Soluble CD30 in patients with antibody-mediated rejection of the kidney allograft (en)
skos:notation	RIV/00023001:_____/07:00001494!RIV08-MZ0-00023001
http://linked.open.../vavai/riv/strany	22-27
http://linked.open...avai/riv/aktivita	N
http://linked.open...avai/riv/aktivity	N
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Lodererová, Alena Honsová, Eva Vítko, Štefan Stříž, Ilja Slavčev, Antonij Sajdlová, Helena Viklický, Ondřej Skibová, Jelena Pavlová, Yelena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	450954
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/07:00001494
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	nephrology; transplantology (en)
http://linked.open.../riv/klicoveSlovo	nephrology transplantology
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[B77FF969B8D6]
http://linked.open...i/riv/nazevZdroje	Transplant Immunology
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	9 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Honsová, Eva Lodererová, Alena Skibová, Jelena Viklický, Ondřej Vítko, Štefan Slavčev, Antonij Stříž, Ilja Pavlová, Yelena Sajdlová, Helena
issn	0966-3274
number of pages	6 (xsd:int)

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