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Description
| - Proton magnetic resonance spectroscopy (1H MRS) is beneficial in the lateralization of the epileptogenic zone in temporal lobe epilepsy; however, its role in extratemporal and, especially, MRI-negative epilepsy has not been established. This study seeks to verify how 1H MRS could help in localizing epileptogenic zone in patients with MRI-negative extratemporal epilepsy. Seven patients (8-23 years) with MRI-negative refractory focal epilepsy were studied using 1H MRS on a 1.5 T MR system. Chemical shift imaging sequence in the transversal plane was directed towards the suspected epileptogenic zone localized by seizure semiology, scalp video/EEG, ictal SPECT and 18FDG-PET. Spectra were evaluated using the program CULICH and the coefficient of asymmetry was used for quantitative lateralization. MRS detected lateralization in all patients and was able to localize pathology in five. The most frequent findings were decreased N-acetylaspartate to choline compounds ratios characterized by increasing choline
- Proton magnetic resonance spectroscopy (1H MRS) is beneficial in the lateralization of the epileptogenic zone in temporal lobe epilepsy; however, its role in extratemporal and, especially, MRI-negative epilepsy has not been established. This study seeks to verify how 1H MRS could help in localizing epileptogenic zone in patients with MRI-negative extratemporal epilepsy. Seven patients (8-23 years) with MRI-negative refractory focal epilepsy were studied using 1H MRS on a 1.5 T MR system. Chemical shift imaging sequence in the transversal plane was directed towards the suspected epileptogenic zone localized by seizure semiology, scalp video/EEG, ictal SPECT and 18FDG-PET. Spectra were evaluated using the program CULICH and the coefficient of asymmetry was used for quantitative lateralization. MRS detected lateralization in all patients and was able to localize pathology in five. The most frequent findings were decreased N-acetylaspartate to choline compounds ratios characterized by increasing choline (en)
- 1H MR spektroskopické zobrazování pacientů s MRI-negativní extratemporální fokální epilepsií. Korelace s iktálním EEG a histopatologií. (cs)
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Title
| - 1H MR spectroscopic imaging in patients with MRI-negative extratemporal focal epilepsy: Correlation with ictal onset zone and histopathology
- 1H MR spektroskopické zobrazování pacientů s MRI-negativní extratemporální fokální epilepsií: Korelace s iktálním EEG a histopatologií. (cs)
- 1H MR spectroscopic imaging in patients with MRI-negative extratemporal focal epilepsy: Correlation with ictal onset zone and histopathology (en)
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skos:prefLabel
| - 1H MR spectroscopic imaging in patients with MRI-negative extratemporal focal epilepsy: Correlation with ictal onset zone and histopathology
- 1H MR spektroskopické zobrazování pacientů s MRI-negativní extratemporální fokální epilepsií: Korelace s iktálním EEG a histopatologií. (cs)
- 1H MR spectroscopic imaging in patients with MRI-negative extratemporal focal epilepsy: Correlation with ictal onset zone and histopathology (en)
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skos:notation
| - RIV/00023001:_____/07:00000777!RIV08-MZ0-00023001
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(NF7411), P(NR8843), Z(MZ0IKEM2005)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00023001:_____/07:00000777
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - MR spectroscopy; Focal cortical dysplasia; MRI; Epilepsy; Surgery (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Komárek, Vladimír
- Marusič, Petr
- Hájek, Milan
- Kršek, Pavel
- Zámečník, Josef
- Dezortová, Monika
- Tichý, Michal
- Škoch, Antonín
- Kynčl, Martin
- Jírů, Filip
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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